Abstract
A prospective study was conducted at the lung cancer clinic of a tertiary care institute to assess the incidence of and reasons for intercycle delays (ICD) during chemotherapy of patients with non-small cell lung cancer (NSCLC). The effect of ICD on overall survival was also assessed. Data were collected for all newly diagnosed NSCLC patients who were initiated on and completed chemotherapy during a 12-month period. Differences between patients who experienced ICD (ICD+ group) versus those who did not (ICD- group) were analyzed. Survival probabilities and median survivals were calculated by Kaplan-Meier method, and group differences were analyzed using the log-rank test. Of the 118 chemonaive NSCLC patients who received chemotherapy, 100 received > or =2 cycles and were included in data analysis. A total of 441 cycles were administered with ICD amounting to 683 days being noted during 84 (19.1%) cycles in 57 patients. The most common reasons for ICD were nonavailability of blood tests reports (25.5%), severe anemia (20.2%), and hospital holidays on scheduled days of chemotherapy (9.6%). ICD+ and ICD- groups did not differ with respect to age, gender, smoking status, histology, stage of disease, baseline performance status, chem...Continue Reading
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Citations
May 16, 2013·Medical Oncology·Navneet SinghDigambar Behera
Jun 27, 2012·Medicine·Navneet SinghAmod Gupta
Nov 8, 2014·Lung India : Official Organ of Indian Chest Society·Navneet Singh, Digambar Behera
Nov 22, 2015·Clinical Lung Cancer·Navneet SinghDigambar Behera
May 18, 2016·Lung India : Official Organ of Indian Chest Society·Venkata Nagarjuna MaturuDigambar Behera
Sep 9, 2016·South Asian Journal of Cancer·Vanita NoronhaKumar Prabhash
Dec 5, 2017·Indian Journal of Cancer·H KaurN Singh
Mar 3, 2019·Cancer·Navneet SinghRakesh Kapoor
Dec 20, 2012·Expert Review of Anticancer Therapy·Navneet SinghDigambar Behera
Aug 5, 2014·American Journal of Clinical Oncology·Navneet SinghDigambar Behera
May 11, 2016·Journal of Global Oncology·Potsangbam Sarat SinghNavneet Singh
Oct 14, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·M N YoganandaNavneet Singh
Aug 24, 2017·Journal of Global Oncology·Lakshimikant Baburao YengeNavneet Singh
Nov 15, 2018·World Journal of Clinical Oncology·Kuruswamy Thurai PrasadNavneet Singh