Interdependence of Primary Metabolism and Xenobiotic Mitigation Characterizes the Proteome of Bjerkandera adusta during Wood Decomposition

Applied and Environmental Microbiology
S C MoodyD C Eastwood

Abstract

The aim of the current work was to identify key features of the fungal proteome involved in the active decay of beechwood blocks by the white rot fungus Bjerkandera adusta at 20°C and 24°C. A combination of protein and domain analyses ensured a high level of annotation, which revealed that while the variation in the proteins identified was high between replicates, there was a considerable degree of functional conservation between the two temperatures. Further analysis revealed differences in the pathways and processes employed by the fungus at the different temperatures, particularly in relation to nutrient acquisition and xenobiotic mitigation. Key features showing temperature-dependent variation in mechanisms for both lignocellulose decomposition and sugar utilization were found, alongside differences in the enzymes involved in mitigation against damage caused by toxic phenolic compounds and oxidative stress.IMPORTANCE This work was conducted using the wood decay fungus B. adusta, grown on solid wood blocks to closely mimic the natural environment, and gives greater insight into the proteome of an important environmental fungus during active decay. We show that a change in incubation temperature from 20°C to 24°C altered the ...Continue Reading

References

May 10, 1991·Science·M I SimonN Gautam
Jan 30, 2002·Cellular and Molecular Life Sciences : CMLS·D Li, R Roberts
Jan 4, 2003·Nature·Zhenglong GuWen-Hsiung Li
Mar 24, 2004·Journal of Structural Biology·Sukyeong LeeFrancis T F Tsai
Apr 20, 2004·Current Opinion in Structural Biology·Christine VogelSarah A Teichmann
May 4, 2004·Nature Biotechnology·Diego MartinezDaniel Rokhsar
Nov 23, 2006·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Roberto Perez-TorradoPierre-Antoine Defossez
Feb 8, 2007·Proceedings of the National Academy of Sciences of the United States of America·Richard HarrisonDaniela Delneri
Jul 4, 2007·Journal of Cell Science·Carolina Perez CastroRik Derynck
Sep 16, 2008·FEMS Microbiology Letters·Ekaterina Shelest
Apr 21, 2009·Applied and Environmental Microbiology·Amber Vanden WymelenbergDan Cullen
Oct 20, 2009·Applied and Environmental Microbiology·Marc AuffretFrançoise Fayolle-Guichard
Feb 23, 2010·Journal of Basic Microbiology·Taina K LundellKristiina Hildén
Jan 1, 2009·Genome Biology and Evolution·Zhi Wang, Jianzhi Zhang
May 10, 2011·Applied and Environmental Microbiology·Amber Vanden WymelenbergDan Cullen
Dec 14, 2011·Microbiological Research·Margarita Rodríguez-KesslerJosé Ruiz-Herrera
Jan 3, 2013·Microbial Biotechnology·Mélanie MorelEric Gelhaye
Aug 13, 2013·Mycologia·Manfred BinderDavid S Hibbett
Feb 11, 2014·Critical Reviews in Biotechnology·Antonio D MorenoMercedes Ballesteros
Jun 25, 2014·Proceedings of the National Academy of Sciences of the United States of America·Robert RileyIgor V Grigoriev
Aug 12, 2014·Applied and Environmental Microbiology·Anne ThuillierMélanie Morel-Rouhier
Sep 27, 2014·Global Change Biology·Kristina J Anderson-TeixeiraJess Zimmerman
Feb 5, 2015·The FEBS Journal·Loredano PollegioniElena Rosini
Jul 29, 2015·Applied Microbiology and Biotechnology·Julia WinkelblechShu-Ming Li
Aug 22, 2015·Journal of Natural Products·Kang ZhouShu-Ming Li
Oct 2, 2015·PloS One·Aurélie DeroyEric Gelhaye
Dec 3, 2016·Nucleic Acids Research·Robert D FinnAlex L Mitchell
Dec 3, 2016·Nucleic Acids Research·Aron Marchler-BauerStephen H Bryant
Jan 29, 2017·Applied and Environmental Microbiology·Gerald N Presley, Jonathan S Schilling

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Methods Mentioned

BETA
GTPase

Software Mentioned

Mascot
InterPro
adusta
CDD
SPARCLE
BLASTP

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