Interdependence of spatial properties and projection patterns of medial vestibulospinal tract neurons in the cat

Journal of Neurophysiology
S I PerlmutterB W Peterson

Abstract

Activity of vestibular nucleus neurons with axons in the ipsi- or contralateral medial vestibulospinal tract was studied in decerebrate cats during sinusoidal, whole-body rotations in many planes in three-dimensional space. Antidromic activation of axon collaterals distinguished between neurons projecting only to neck segments from those with collaterals to C6 and/or oculomotor nucleus. Secondary neurons were identified by monosynaptic activation after labyrinth stimulation. A three-dimensional maximum activation direction vector (MAD) summarized the spatial properties of 151 of 169 neurons. The majority of secondary neurons (71%) terminated above the C6 segment. Of these, 43% had ascending collaterals to the oculomotor nucleus (VOC neurons), and 57% did not (VC neurons). The majority of VOC and VC neurons projected contralaterally and ipsilaterally, respectively. Most C6-projecting neurons could not be activated from oculomotor nucleus (V-C6 neurons) and projected primarily ipsilaterally. All VO-C6 neurons projected contralaterally. The distributions of MADs for secondary neurons with different projection patterns were different. Most VOC (84%) and contralaterally projecting VC (91%) neurons had MADs close to the activation ve...Continue Reading

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Citations

Apr 2, 2004·Journal of Neurophysiology·Andrea M Green, Dora E Angelaki
Apr 23, 2020·Journal of Neurophysiology·Etienne GuillaudJean-René Cazalets
Aug 13, 1999·Journal of Neurophysiology·S I PerlmutterB W Peterson
Sep 30, 2005·Journal of Neurophysiology·Sergei B YakushinBernard Cohen
Apr 12, 2017·Frontiers in Neurology·Andrew A McCallBill J Yates
Dec 6, 2002·Journal of Neurophysiology·J David Dickman, Dora E Angelaki
Nov 17, 2001·Annals of the New York Academy of Sciences·B W PetersonG C Peng

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