Interfacial dynamic adsorption and structure of molecular layers of peptide surfactants

Langmuir : the ACS Journal of Surfaces and Colloids
Fang PanJohn R P Webster

Abstract

Short peptide surfactants have recently emerged as a new class of amphiphiles, with tremendous potential in improving surface biocompatibility and mediating interfacial DNA immobilization. To establish their basic interfacial adsorption properties, cationic peptide surfactants V(m)K(n) have been studied by combining the measurements of spectroscopic ellipsometry (SE), neutron reflection (NR) and atomic force microscopy (AFM). Our results showed that changes in peptide structure, concentration, solution pH and ionic strength all affected their interfacial assembly. Increases in m and decreases in n reduced the critical aggregation concentration (CAC), but increased the amount of adsorption, showing the strong influence of the amphiphilic balance between hydrophilic and hydrophobic moieties. While the surface adsorbed amount increased with time and peptide concentration, an increase in ionic strength decreased peptide adsorption due to surface charge neutralization. Changes in solution pH did not affect the equilibrium surface adsorbed amount on the weakly negative SiO(2) surface, but did alter the adsorption dynamics. Neutron reflection revealed that V(6)K readily formed a bilayer structure of 35 A thickness at the interface, wi...Continue Reading

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Citations

May 27, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Xiubo ZhaoJikui Luo
May 26, 2010·Chemical Society Reviews·Xiubo ZhaoJian R Lu
Dec 19, 2014·Journal of Colloid and Interface Science·Masayoshi TanakaTakatoshi Kinoshita
Jul 29, 2016·Langmuir : the ACS Journal of Surfaces and Colloids·Dharana JayawardaneXiubo Zhao
Feb 23, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Qingbin MengKeliang Liu
Dec 8, 2017·ACS Applied Materials & Interfaces·Fang PanJian Ren Lu
Dec 1, 2018·ACS Applied Materials & Interfaces·Zongyi LiJian Ren Lu
Sep 25, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Fang PanXiubo Zhao

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