Interfacial energy of polypeptide complex coacervates measured via capillary adhesion

Langmuir : the ACS Journal of Surfaces and Colloids
Dimitrios PriftisMatthew Tirrell

Abstract

A systematic study of the interfacial energy (γ) of polypeptide complex coacervates in aqueous solution was performed using a surface forces apparatus (SFA). Poly(L-lysine hydrochloride) (PLys) and poly(L-glutamic acid sodium salt) (PGA) were investigated as a model pair of oppositely charged weak polyelectrolytes. These two synthetic polypeptides of natural amino acids have identical backbones and differ only in their charged side groups. All experiments were conducted using equal chain lengths of PLys and PGA in order to isolate and highlight effects of the interactions of the charged groups during complexation. Complex coacervates resulted from mixing very dilute aqueous salt solutions of PLys and PGA. Two phases in equilibrium evolved under the conditions used: a dense polymer-rich coacervate phase and a dilute polymer-deficient aqueous phase. Capillary adhesion, associated with a coacervate meniscus bridge between two mica surfaces, was measured upon the separation of the two surfaces. This adhesion enabled the determination of the γ at the aqueous/coacervate phase interface. Important experimental factors affecting these measurements were varied and are discussed, including the compression force (1.3-35.9 mN/m) and separa...Continue Reading

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Citations

Sep 26, 2013·Acta Biomaterialia·Wei WeiJ Herbert Waite
Jan 15, 2015·Nature Communications·Sarah L PerryMatthew Tirrell
Oct 23, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Dimitrios PriftisMatthew Tirrell
Feb 3, 2016·Proceedings of the National Academy of Sciences of the United States of America·Sangsik KimDong Soo Hwang
Sep 10, 2015·Angewandte Chemie·Dimitrios PriftisMatthew Tirrell
Dec 1, 2015·ACS Biomaterials Science & Engineering·Dusty Rose MillerJ Herbert Waite
Nov 26, 2013·Advances in Colloid and Interface Science·Gregory Dardelle, Philipp Erni
May 7, 2016·Journal of Colloid and Interface Science·F MousseauJ-F Berret
May 11, 2016·Advances in Colloid and Interface Science·Charles E Sing
Jul 16, 2016·Advances in Colloid and Interface Science·Amanda B MarcielLorraine Leon
Aug 9, 2016·Advances in Colloid and Interface Science·YongSeok JhoDong Soo Hwang
Sep 17, 2016·Advances in Colloid and Interface Science·Yalin LiuSarah L Perry
Feb 24, 2017·Nature Communications·Samanvaya SrivastavaMatthew V Tirrell
Sep 5, 2017·Organic & Biomolecular Chemistry·Brandon M JohnstonSarah L Perry
Nov 9, 2019·Chemical Communications : Chem Comm·Baishakhi SahaDibyendu Das
Mar 7, 2020·Soft Matter·Charles E Sing, Sarah L Perry
May 5, 2020·Small·Whitney C Blocher McTigue, Sarah L Perry
Sep 9, 2020·Physical Chemistry Chemical Physics : PCCP·Whitney C Blocher McTigueSarah L Perry
Oct 3, 2020·Small·Qiongyao PengHongbo Zeng
Nov 6, 2018·The Journal of Chemical Physics·Tyler K LytleCharles E Sing
Dec 13, 2017·Soft Matter·Ana Maria Bago RodriguezTomoko Sekine
Nov 6, 2018·The Journal of Chemical Physics·Mengmeng Zhao, Nicole S Zacharia
Nov 5, 2016·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Whitney C Blocher, Sarah L Perry
Aug 16, 2018·Soft Matter·Byoung-Jin JeonOmar A Saleh
Nov 24, 2020·Macromolecular Rapid Communications·Xiaoming XieWen Li
Apr 12, 2018·Biophysical Journal·Patrick M McCallMatthew V Tirrell
Jun 26, 2021·Physical Review Letters·Debra J AudusVivek M Prabhu
Jul 31, 2021·ACS Applied Materials & Interfaces·Xiufeng LiRenko de Vries
Jan 1, 2018·ACS Macro Letters·Marat AndreevJuan J de Pablo
Aug 20, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Sohee ParkDong Soo Hwang
Apr 3, 2020·ACS Nano·Mart G F LastCees Dekker
Mar 3, 2020·ACS Applied Materials & Interfaces·Xiufeng LiRenko de Vries
Jan 22, 2020·Journal of the American Chemical Society·Tiemei Lu, Evan Spruijt

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