Interfacial organic synthesis in a simple droplet-based microfluidic system

Lab on a Chip
Ji JiPengyuan Yang

Abstract

A spherical liquid-liquid interface can be obtained by dispersing one liquid phase into another to form droplets, which will facilitate the two-phase reactions between the immiscible participating fluids. The phase transfer catalysts assembled at the droplet "wall" catalyze the reactions between the aqueous and organic phases. The study illustrates an interfacial synthetic approach which is ideal for the biphasic reaction by taking advantage of the droplet-based microdevice. The improved reaction efficiency can be attributed to the high surface-to-volume ratio and internal flow circulation in the droplets.

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Citations

Dec 29, 2015·Chemical Reviews·Keti PiradashviliKatharina Landfester
Mar 16, 2016·Langmuir : the ACS Journal of Surfaces and Colloids·Kai WangGuangsheng Luo
Jun 10, 2015·Lab on a Chip·Thomas W PhillipsJohn C deMello
Jul 16, 2016·Nano Letters·Julian SchüttGianaurelio Cuniberti
Aug 17, 2016·Biosensors·Brigitte BruijnsHan Gardeniers
Jun 18, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Shingo MiuraTaro Toyota
Jun 19, 2013·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·J Guadarrama-Cetina, W González-Viñas
Apr 24, 2021·Scientific Reports·K I BelousovA S Bukatin

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