PMID: 8586524Jan 1, 1995Paper

Interferon alpha therapy for chronic active hepatitis type C after renal transplantation and allograft rejection

International Urology and Nephrology
S TakaharaA Okuyama

Abstract

An acute type rejection episode occurred in one of two patients treated with Interferon alpha (IFN alpha) for type C hepatitis (CHC). Histopathological examination of the graft kidney revealed focal cellular infiltration and chronic transplant glomerulopathy which showed acute or chronic type rejection. In spite of bolus administration of methyl-prednisolone, the elevation of serum creatinine level continued. After administration of anti-human lymphocyte globulin (AHLG), renal function improved, but urinary protein was still positive. Another patient had no episode of rejection during or after IFN alpha therapy.

References

Dec 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·I HeronK Berg
Jan 1, 1987·Annual Review of Biochemistry·S PestkaC E Samuel
Nov 30, 1989·The New England Journal of Medicine·A M Di BisceglieJ H Hoofnagle
Apr 20, 1985·British Medical Journal·P SelbyT McElwain
Apr 20, 1985·British Medical Journal·D M Davies

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Citations

Feb 24, 2004·Drugs·Susan E ChanHugo R Rosen
Nov 4, 2006·Alimentary Pharmacology & Therapeutics·F FabriziP Martin
Nov 4, 2008·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·C H CookC G Orosz
Apr 19, 2002·Journal of the American Society of Nephrology : JASN·Marjan AfrouzianPhilip F Halloran

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