PMID: 43690Aug 1, 1979

Interferon induced in the hamster by subunits of "Nocardia": essay of protection against rabies (author's transl)

Annales de microbiologie
R Barot-CiorbaruP Atanasiu


Lipid-free cells of Nocardia opaca and a cell extract (NWSM) are interferon inducers in syrian hamsters: peak interferon appears 2 h after injection as compared to 8 h in the case of interferon induced by inactivated NDV virus. The interferon induced by Nocardia product is inactivated by a treatment for 30 min at 56 degrees C or 24 h at pH 2: NDV-induced interferon is more stable under these conditions. Hamsters inoculated with NWSM before and after infection with rabies virus are partially protected: their survival time is slightly increased.

Related Concepts

Rabies virus
Mesocricetus auratus
Newcastle disease virus
Human leukocyte interferon
Allergy Testing Hamster
Interferon Inducers

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