Interferon production by a human lymphoblastoid cell line (DG-75) free of the Epstein-Barr genome.

Antimicrobial Agents and Chemotherapy
A LazarA Mizrahi

Abstract

A new lymphoblastoid cell line, DG-75, was investigated for its ability to produce interferon. DG-75 cells, previously shown to be free of Epstein-Barr virus genome and receptors, could be grown in submerged culture and could produce interferon in titers comparable to interferon produced by Namalva cells. The interferon produced was similar in size to the Namalva interferon as determined by gel filtration in Ultrogel AcA54. The DG-75 cells present a new source of large quantities of interferon which may be safer for human use than the Namalva interferon.

References

Feb 15, 1975·International Journal of Cancer. Journal International Du Cancer·K Nilsson, J Pontén
Jan 1, 1977·International Journal of Cancer. Journal International Du Cancer·H Ben-BassatG Klein
Sep 18, 1977·Blut·H Strander
Dec 1, 1979·Cancer Treatment Reviews·T J Priestman
Mar 1, 1979·Antimicrobial Agents and Chemotherapy·F KleinP J Bridgen
Jul 15, 1972·International Journal of Cancer. Journal International Du Cancer·G KleinB Gothoskar
Dec 1, 1972·Antimicrobial Agents and Chemotherapy·E A Havell, J Vilcek
Mar 1, 1973·Archives of Biochemistry and Biophysics·P BöhlenS Udenfriend

❮ Previous
Next ❯

Related Concepts

Related Feeds

CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

Related Papers

Cytometry. Part a : the Journal of the International Society for Analytical Cytology
Sanjai Nagendra, Annette J Schlueter
The New England Journal of Medicine
Christopher M ParryJeremy J Farrar
© 2021 Meta ULC. All rights reserved