Interferon, the oxytocin receptor and the maternal recognition of pregnancy in ruminants and non-ruminants: a comparative approach

Reproduction, Fertility, and Development
A P Flint

Abstract

Ruminant and non-ruminant members of the Artiodactyla appear to use different mechanisms for the maternal recognition of pregnancy. In ruminants, the trophoblast of the developing blastocyst produces a characteristic Type I interferon of the interferon-tau family; this acts by blocking endometrial synthesis of the oxytocin receptor. A similar mechanism applies to domestic ruminants (sheep, cow, goat) and deer. In roe deer, which have embryonic diapause and are monoestrus, there is no requirement for a pre-implantation blastocyst signal to ensure maternal recognition of pregnancy. This paper compares the mechanisms leading to the maternal recognition of pregnancy in ruminants with that suggested to occur in a non-ruminant (the domestic pig).

Citations

Jun 16, 2005·The Veterinary Clinics of North America. Food Animal Practice·E Keith Inskeep, Robert A Dailey
Jan 5, 2002·Theriogenology·W W ThatcherJ K Pru
Mar 29, 2000·Theriogenology·C E Rexroad, A M Powell
Jun 14, 2000·Animal Reproduction Science·D C Sharp
Apr 12, 2002·Animal Reproduction Science·W Caroline Lo, P M Summers
Jul 11, 2002·Animal Reproduction Science·Mehmet Akif CamErdogan Selcuk
Jan 7, 1999·Animal Reproduction Science·J J Ramsoondar, R J Christopherson
Jun 27, 2003·Trends in Endocrinology and Metabolism : TEM·Hans H Zingg, Stephane A Laporte
Oct 19, 2004·Development and Psychopathology·David SchultzGeorge Bear
Apr 15, 2006·Development and Psychopathology·Nicki R CrickKathleen Woods
Jan 24, 2007·Development and Psychopathology·Sylvana M CôtéRichard E Tremblay
Jan 24, 2007·Development and Psychopathology·Pamela W Garner, Elizabeth A Lemerise
Aug 1, 2008·Animal : an International Journal of Animal Bioscience·P C GarnsworthyR Webb
Aug 28, 2012·The Journal of Genetic Psychology·Nicole E Werner
Jan 1, 1997·American Journal of Reproductive Immunology : AJRI·J D GodkinJ J Doré
Jun 1, 1997·American Journal of Reproductive Immunology : AJRI·F W BazerT L Ott
Sep 25, 2002·Proceedings of the National Academy of Sciences of the United States of America·Renée M Tsolis
Feb 20, 2007·Annals of the New York Academy of Sciences·Panagiotis BeretsosAris Antsaklis
Feb 24, 2006·The Veterinary Journal·C W WeemsR D Randel
Mar 9, 2007·Biology of Reproduction·Ali A Fouladi-NashtaRobert Webb

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