Interferon treatment for corneolimbal squamous dysplasia

American Journal of Ophthalmology
F R HuS H Kuo

Abstract

To report a patient with corneolimbal squamous dysplasia successfully treated with interferon therapy. A 78-year-old man had a gelatinous and vascularized lesion involving the left cornea and adjacent limbus. Impression cytology studied with periodic acid--Schiff-hematoxylin stain disclosed severe squamous dysplasia. Topical instillation and subconjunctival injection of interferon alpha-2b was instituted. The gelatinous tumor mass involving the cornea and adjacent limbus completely resolved 2 months after interferon treatment. He showed no sign of recurrence during the 10-month follow-up. Interferon therapy may be a therapeutic alternative for treating corneolimbal squamous dysplasia.

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Citations

Jun 19, 2003·The British Journal of Ophthalmology·T W Reid, N Dushku
Jul 20, 2007·The British Journal of Ophthalmology·Anthony J Aldave, Anne Nguyen
Mar 5, 2002·Ophthalmology·Joseph Frucht-PeryJacob Pe'er
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Nov 1, 2006·The Ocular Surface·Joann A Giaconi, Carol L Karp
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Jan 7, 2009·International Ophthalmology Clinics·Rola HamamCharles Stephen Foster
Feb 12, 2017·Expert Review of Ophthalmology·Ibrahim O Sayed-AhmedCarol L Karp

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