Jan 1, 1988

Interferonogenic and antiviral effect of extracts from Erodium cicutarium. II. Modulatory activity of Erodium cicutarium extracts

Archivum Immunologiae Et Therapiae Experimentalis
J Zielińska-JenczylikH Rzadkowska-Bodalska

Abstract

Methanol extract from Erodium cicutarium was shown not to induce interferon in a suspension of human leukocytes or in the cutaneo-muscular tissue of human embryo. It appeared to have no influence, either direct or cell-mediated, on interferon activity. However, it exerted stimulatory effect on the synthesis of interferon induced with Newcastle disease virus in cell cultures. The stimulation occurred irrespective of the time of methanol extract administration (before or after viral inducer). In the in vivo experiments, methanol extract injected intravenously induced interferon in mice. When given 24 h prior to Newcastle virus, it increased the titer of induced interferon determined in the animal serum collected 6 h after the virus injection. Besides, in the experimental viral infection in mice replication of influenza A virus in the lung tissue of infected animals was inhibited only when the mice were treated with methanol extract 24 and 48 h after infection with the virus.

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Newcastle disease virus
Exertion
Virus Diseases
Cell Culture Techniques
Influenza
White Blood Cell Count Procedure
Human leukocyte interferon
Phytotherapy
Interferon
Leukocytes

About this Paper

Related Feeds

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Related Papers

Archivum Immunologiae Et Therapiae Experimentalis
J Zielińska-Jenczylik, A Sypuła
Archivum Immunologiae Et Therapiae Experimentalis
J Zielińska-JenczylikH Rzadkowska-Bodalska
Zeitschrift Für Naturforschung. C, a Journal of Biosciences
Z SrokaI Mazol
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Haibo YinGuoyu Li
© 2020 Meta ULC. All rights reserved