Intergenerational Transfer of Epigenetic Information in Sperm

Cold Spring Harbor Perspectives in Medicine
Oliver J Rando

Abstract

The inheritance of information beyond DNA sequence, known as epigenetic inheritance, has been implicated in a multitude of biological processes from control of plant flowering time to cancer in humans. In addition to epigenetic inheritance that occurs in dividing cells of a multicellular organism, it is also increasingly clear that at least some epigenetic information is transmitted via the gametes in a multitude of organisms, including mammals. Here, I review the evidence for epigenetic information carriers in mammalian sperm, and explore the emerging field of intergenerational transfer of environmental information.

Citations

Apr 27, 2018·Systems Biology in Reproductive Medicine·Marta GòdiaAlex Clop
Mar 8, 2018·Biology of Reproduction·Marta GòdiaStephen A Krawetz
Dec 10, 2017·Nature Communications·Raquel Chamorro-GarciaBruce Blumberg
Jul 7, 2018·Epigenomics·Brandon L PearsonDan Ehninger
Jun 8, 2018·Biology of Reproduction·John C Schimenti, Mary Ann Handel
Jul 28, 2017·Reproduction : the Official Journal of the Society for the Study of Fertility·Yue Liu, Zhide Ding
Dec 6, 2017·Journal of Molecular Endocrinology·Louise Ruby Høj IllumAnders Lade Nielsen
Sep 8, 2018·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Rachel Yehuda, Amy Lehrner
Dec 26, 2018·Journal of Neuroendocrinology·Hirotaka Hamada, Stephen G Matthews
Dec 27, 2019·PLoS Biology·Daniel NättAnita Öst
Feb 12, 2020·Biological Reviews of the Cambridge Philosophical Society·Guilherme JeremiasJana Asselman
Aug 29, 2019·Proceedings. Biological Sciences·Ilaria SciamannaCorrado Spadafora
Feb 23, 2018·Nature·George C PattonSusan M Sawyer
Feb 26, 2016·Journal of Cellular Physiology·Desiree TilloCharles Vinson
Nov 18, 2017·Toxicological Sciences : an Official Journal of the Society of Toxicology·Roger GodschalkFrederik Jan van Schooten
Sep 20, 2018·Molecular Genetics and Genomics : MGG·Line Katrine KlastrupAnders Lade Nielsen
Aug 14, 2019·Genome Biology and Evolution·Boris YagoundEmily J Remnant
Jan 21, 2017·Current Opinion in Endocrinology, Diabetes, and Obesity·Alan D AttieJoseph H Nadeau
Apr 25, 2018·Nature Reviews. Molecular Cell Biology·Melanie A Eckersley-MaslinWolf Reik
Aug 9, 2020·Journal of Clinical Medicine·Matilde CesconRenata S Tavares
Jul 1, 2018·Heredity·Simone Immler
May 1, 2020·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Daniela KasparJohannes Beckers
Jun 25, 2016·The Journal of Endocrinology·Menghong Yan, Qiwei Zhai
Nov 3, 2016·Proceedings of the National Academy of Sciences of the United States of America·Julia MarréAntony M Jose
Mar 2, 2017·Nature Cell Biology·Kiyomi R Kaneshiro, Susan Strome
Jul 30, 2019·Epigenetics : Official Journal of the DNA Methylation Society·Grace M SwansonStephen A Krawetz
Dec 13, 2018·Nature Communications·Denny VågeröGerard J van den Berg
Oct 22, 2019·Current Opinion in Neurobiology·Noa LibermanEric Lieberman Greer
Nov 12, 2020·Frontiers in Genetics·Chongyang Wu, Marc-André Sirard
Feb 13, 2021·American Journal of Reproductive Immunology : AJRI·Sushama RokadeVineeta Bal
Nov 14, 2018·Best Practice & Research. Clinical Endocrinology & Metabolism·Monica Muratori, Christian De Geyter
Apr 20, 2021·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Angela J Crean, Simone Immler
May 1, 2021·Biology of Reproduction·Millissia Ben MaamarMichael K Skinner
May 28, 2021·Frontiers in Cell and Developmental Biology·Mani Arul PrakashTirtha Kumar Datta
Jul 3, 2021·Frontiers in Human Neuroscience·Elsher Lawson-Boyd, Maurizio Meloni
Aug 5, 2021·Development·Nihan OzturkUndraga Schagdarsurengin

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