Interictal Abnormalities of Neuromagnetic Gamma Oscillations in Migraine Following Negative Emotional Stimulation

Frontiers in Behavioral Neuroscience
Ting WuTianzi Jiang

Abstract

Here, we aimed to investigate brain activity in migraineurs in response to emotional stimulation. Magnetoencephalography (MEG) was used to examine 20 patients with episodic migraine (EM group), 15 patients with chronic migraine (CM group), and 35 healthy participants (control group). Neuromagnetic brain activity was elicited by emotional stimulation using photographs of facial expressions. We analyzed the latency and amplitude of M100 and M170 components and used Morlet wavelet and beamformers to analyze the spectral and spatial signatures of MEG signals in gamma band (30-100 Hz). We found that the timing and frequency of MEG activity differed across the three groups in response negative emotional stimuli. First, peak M170 amplitude was significantly lower in the CM group than in the control group. Second, compared with the control group, the average spectral power was significantly lower in the EM group and CM group at M100 and M170. Third, the average spectral powers of the M100 and M170 in the CM group were negatively correlated with either HAM-D scores or migraine attack frequency. No significant differences across groups was found for positive or neutral emotional stimuli. Furthermore, after negative emotional stimuli, the...Continue Reading

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References

May 17, 2002·Current Opinion in Neurobiology·Ralph Adolphs
Aug 10, 2002·NeuroImage·Ruben C GurRaquel E Gur
Aug 27, 2002·Nature Neuroscience·Jia LiuNancy Kanwisher
May 3, 2003·Neuroscience Letters·Marcus StreitAndreas Ioannides
Apr 28, 2004·Pain·A Vania ApkarianDante R Chialvo
Feb 18, 2005·Neuropsychologia·Yaoda XuNancy Kanwisher
Mar 10, 2006·Psychiatry Research·Michael BassoChristopher H van Dyck
Jun 27, 2006·Neuropsychologia·Martin Eimer, Amanda Holmes
Oct 6, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Alexandre SchaeferJeremy R Gray
Jun 14, 2008·Neuron·Ben Seymour, Ray Dolan
Dec 2, 2008·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Rupesh KotechaTon deGrauw
Dec 24, 2008·Journal of Clinical and Experimental Neuropsychology·Jing Xiang, Zheng Xiao
Apr 14, 2009·NeuroImage·Milan BrázdilIvan Rektor
Apr 30, 2009·Annual Review of Neuroscience·Pascal Fries
Sep 4, 2009·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Rami Burstein, M Jakubowski
Jul 1, 2009·Psychiatry Research·Nim TottenhamCharles Nelson
Aug 29, 2009·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Marina de TommasoPaolo Livrea
Nov 26, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Susanne ErkHenrik Walter
Dec 21, 2010·Current Biology : CB·Justin S FeinsteinDaniel Tranel
Apr 21, 2012·The Journal of Pain : Official Journal of the American Pain Society·Atsuo YoshinoShigeto Yamawaki
Nov 8, 2012·Journal of Neurology·Dawn C BuseRichard B Lipton
May 31, 2013·Cephalalgia : an International Journal of Headache·Nouchine HadjikhaniCaterina Mainero
Jun 19, 2013·Cephalalgia : an International Journal of Headache·UNKNOWN Headache Classification Committee of the International Headache Society (IHS)
Jun 25, 2013·The Journal of Pain : Official Journal of the American Pain Society·Jing XiangAndrew D Hershey
Jul 31, 2013·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Erol Başar
Dec 17, 2014·Lancet Neurology·Todd J SchwedtDavid W Dodick
Jul 16, 2016·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Feng LiJingping Shi
Jan 25, 2017·The Journal of Headache and Pain·Zhiye ChenShengyuan Yu
Dec 15, 2017·Cephalalgia : an International Journal of Headache·X Michelle AndroulakisKaitlin Krebs
Mar 17, 2018·AJNR. American Journal of Neuroradiology·J D SantoroK W Yeom

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BrainX
MEG Processor
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