Interictal spikes and epileptic seizures: their relationship and underlying rhythmicity

Brain : a Journal of Neurology
Philippa J KarolyMark J Cook

Abstract

We report on a quantitative analysis of electrocorticography data from a study that acquired continuous ambulatory recordings in humans over extended periods of time. The objectives were to examine patterns of seizures and spontaneous interictal spikes, their relationship to each other, and the nature of periodic variation. The recorded data were originally acquired for the purpose of seizure prediction, and were subsequently analysed in further detail. A detection algorithm identified potential seizure activity and a template matched filter was used to locate spikes. Seizure events were confirmed manually and classified as either clinically correlated, electroencephalographically identical but not clinically correlated, or subclinical. We found that spike rate was significantly altered prior to seizure in 9 out of 15 subjects. Increased pre-ictal spike rate was linked to improved predictability; however, spike rate was also shown to decrease before seizure (in 6 out of the 9 subjects). The probability distribution of spikes and seizures were notably similar, i.e. at times of high seizure likelihood the probability of epileptic spiking also increased. Both spikes and seizures showed clear evidence of circadian regulation and, f...Continue Reading

References

Nov 1, 1991·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·J Gotman
Mar 1, 1991·Epilepsy Research·E TaubøllL Gjerstad
May 5, 1987·Brain Research·H S SwartzwelderW A Wilson
Jan 1, 1980·Progress in Neurobiology·J O McNamaraJ G Fitz
Jun 1, 1980·Epilepsia·M E Newmark, J K Penry
Sep 21, 2000·Epilepsy Research·M Quigg
Sep 21, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·A CrespelM Baldy-Moulinier
Sep 21, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·F FerrilloL Nobili
Feb 13, 2001·Progress in Neurobiology·M de Curtis, G Avanzini
Jul 24, 2001·Seizure : the Journal of the British Epilepsy Association·J Bauer, W Burr
Dec 5, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Scott B Wilson, Ronald Emerson
Feb 26, 2003·Annals of Neurology·Laura Librizzi, Marco de Curtis
Jun 1, 1960·Epilepsia·A A WARD
Apr 1, 1964·Experimental Neurology·H MATSUMOTO, C A MARSAN
Sep 10, 1964·Annals of the New York Academy of Sciences·N A BERCEL
Feb 22, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·S KalitzinF Lopes da Silva
Apr 4, 2006·Lancet·John S DuncanMatthew C Walker
Jan 30, 2007·Epilepsy Currents·Massimo AvoliM de Curtis
Sep 5, 2008·PLoS Computational Biology·Gustavo DecoKarl Friston
Mar 3, 2009·Brain : a Journal of Neurology·Radwa BadawySamuel Berkovic
Oct 14, 2009·The European Journal of Neuroscience·Ivan OsorioJohn Milton
Dec 7, 2011·Epilepsy & Behavior : E&B·Dean R FreestoneMark J Cook
Jun 22, 2012·Annals of Neurology·Laetitia ChauvièreChristophe Bernard
Nov 26, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Nicolas GaspardHitten P Zaveri
Aug 15, 2014·PLoS Computational Biology·Yujiang WangGerold Baier
Dec 17, 2014·Frontiers in Neuroscience·Dean R FreestoneDavid B Grayden
Oct 16, 2015·Journal of Mathematical Neuroscience·Sergej O VoronenkoBenjamin Lindner

❮ Previous
Next ❯

Citations

Jul 13, 2016·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Bassel Abou-Khalil
Aug 30, 2016·The International Journal of Neuroscience·Bo JinMeiping Ding
Oct 12, 2016·Epilepsy & Behavior : E&B·Udaya SeneviratneWendyl D'Souza
Dec 10, 2016·Epilepsia·Peter C HorakBarbara C Jobst
Jan 14, 2017·Epilepsia·Philippa J KarolyRay Boston
Jan 25, 2017·Current Opinion in Neurology·Dean R FreestoneMark J Cook
Jan 20, 2018·Physical Review. E·M A LopesA V Goltsev
Jan 26, 2018·Current Opinion in Neurology·Philippa KarolyMark Cook
Mar 23, 2019·Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko·M B KorsakovaE M Troshina
Feb 23, 2019·Journal of Neural Engineering·M Dümpelmann
Apr 9, 2019·Journal of Neural Engineering·Petr NejedlyGregory A Worrell
Sep 14, 2017·Brain : a Journal of Neurology·Philippa J KarolyDean R Freestone
Dec 21, 2019·Brain : a Journal of Neurology·Erin C ConradEric D Marsh
Dec 31, 2019·Clinical EEG and Neuroscience·Marjan AsadollahiLeila Simani
Oct 26, 2018·Neurology·Maxime O Baud, Vikram R Rao
Feb 13, 2020·Current Opinion in Neurology·Maxime O BaudKaspar Schindler
Aug 2, 2020·Epilepsia·Vikram R RaoMaxime O Baud
Jan 10, 2018·Nature Communications·Maxime O BaudVikram R Rao
Oct 14, 2018·Journal of Computational Neuroscience·Patrick LuckettJuan Ochoa
Dec 15, 2018·Neuromodulation : Journal of the International Neuromodulation Society·Toni KuljuJukka Peltola
Nov 30, 2019·Frontiers in Neurology·Irina GurevicieneHeikki Tanila
Oct 3, 2019·Physical Review. E·F DeebaP A Robinson
May 3, 2020·Nature Communications·Matias I MaturanaDean R Freestone
Dec 19, 2018·Scientific Reports·Jordan S FarrellG Campbell Teskey
Oct 3, 2019·Chaos·Theresa WilkatKlaus Lehnertz
Sep 29, 2019·Current Treatment Options in Neurology·Katrina L DellMatias I Maturana
Apr 22, 2020·Epilepsy Currents·David King-Stephens
Mar 13, 2020·Brain Communications·Nicholas M GreggGregory A Worrell
May 3, 2020·Proceedings of the National Academy of Sciences of the United States of America·Christian Meisel
May 16, 2020·Frontiers in Neurology·Magdalena K Smyk, Gilles van Luijtelaar
Jul 28, 2020·Epilepsia·Rachel E StirlingPhilippa J Karoly
Aug 23, 2018·Nature Reviews. Neurology·Levin KuhlmannHitten P Zaveri
Sep 19, 2020·Epilepsia·John P AndrewsEdward F Chang
Oct 24, 2018·Nature Reviews. Neurology·Iván Sánchez Fernández, Tobias Loddenkemper

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved