Interleaved 3D-CNNs for joint segmentation of small-volume structures in head and neck CT images

Medical Physics
Xuhua RenQian Wang

Abstract

Accurate 3D image segmentation is a crucial step in radiation therapy planning of head and neck tumors. These segmentation results are currently obtained by manual outlining of tissues, which is a tedious and time-consuming procedure. Automatic segmentation provides an alternative solution, which, however, is often difficult for small tissues (i.e., chiasm and optic nerves in head and neck CT images) because of their small volumes and highly diverse appearance/shape information. In this work, we propose to interleave multiple 3D Convolutional Neural Networks (3D-CNNs) to attain automatic segmentation of small tissues in head and neck CT images. A 3D-CNN was designed to segment each structure of interest. To make full use of the image appearance information, multiscale patches are extracted to describe the center voxel under consideration and then input to the CNN architecture. Next, as neighboring tissues are often highly related in the physiological and anatomical perspectives, we interleave the CNNs designated for the individual tissues. In this way, the tentative segmentation result of a specific tissue can contribute to refine the segmentations of other neighboring tissues. Finally, as more CNNs are interleaved and cascaded...Continue Reading

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Citations

Nov 23, 2018·Physics in Medicine and Biology·Meghan W MacomberMatthew J Nyflot
Dec 13, 2018·Physics in Medicine and Biology·Haibin ChenXuejun Gu
Jan 24, 2020·Physics in Medicine and Biology·Chenyang ShenXun Jia
Feb 12, 2020·Physics in Medicine and Biology·Yi XueTianye Niu
Jul 11, 2020·Medical Physics·Yingzi LiuXiaofeng Yang
Aug 21, 2018·Journal of Healthcare Engineering·Hiroyuki Sugimori
Jul 28, 2019·International Journal of Computer Assisted Radiology and Surgery·Trevor J HuffJustin A Cramer
Mar 9, 2019·International Journal of Computer Assisted Radiology and Surgery·Elias TappeinerKarl Fritscher
Jun 20, 2020·International Journal of Computer Assisted Radiology and Surgery·Elias TappeinerRainer Schubert
Dec 10, 2019·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Jordan WongAbraham Alexander
Jun 3, 2021·Journal of Personalized Medicine·Bingjiang QiuPeter M A van Ooijen
May 17, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Yabo FuXiaofeng Yang
Jun 3, 2021·Journal of Personalized Medicine·Bingjiang QiuPeter M A van Ooijen
Jul 3, 2021·Journal of Personalized Medicine·Bingjiang QiuPeter M A van Ooijen
Oct 10, 2021·Nature Communications·Shanshan WangHairong Zheng

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