PMID: 9527355Apr 4, 1998Paper

Interleukin-1beta in plasma and synovial fluid in relation to radiographic changes in arthritic temporomandibular joints

European Journal of Oral Sciences
S NordahlS Kopp

Abstract

The aim of this study was to investigate the level of the cytokine IL-1beta in plasma and temporomandibular joint (TMJ) synovial fluid of patients with arthropathies, and to study the relation between IL-1beta levels of synovial fluid and plasma as well as radiographic changes of the TMJ. 31 patients with general disease, 14 with rheumatoid arthritis (RA) and 17 with various arthritides were included in the study. Synovial fluid and blood samples were collected, and an individualized tomography of the TMJ was performed. Detectable levels of IL-1beta were found in 5 out of 39 synovial fluids and in 10 out of 27 plasma samples. The presence of IL-1beta in both plasma and synovial fluid was more frequent in RA patients than in the non-RA group. The extension of radiographic erosion was significantly greater in joints with IL-1beta than in those without. Both the extension of erosion and grade of radiographic changes of the TMJ were greater in patients with detectable IL-1beta level of plasma than in patients without. Our study indicates that presence of IL-1beta in plasma and synovial fluid is related to radiographic changes of the TMJ.

Citations

Apr 20, 2001·Archives of Oral Biology·K TominagaS Kopp
May 22, 2003·Pharmacology, Biochemistry, and Behavior·C A KerinsL L Bellinger
Oct 31, 2003·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Per AlstergrenSigvard Kopp
Mar 19, 2002·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Manabu HabuJinichi Fukuda
Jun 1, 2013·The Journal of Pain : Official Journal of the American Pain Society·Hong ChenWilliam Maixner
Oct 22, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Michael J GunsonStephen B Milam
Oct 20, 2009·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Gary F Bouloux
Mar 14, 2008·The Journal of Pain : Official Journal of the American Pain Society·James R Morgan, G F Gebhart
Aug 22, 2007·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Po-Wei LinChi-Hsien Chen
Mar 1, 2014·Journal of Oral Rehabilitation·K D KristensenT K Pedersen
May 15, 2003·Arthritis and Rheumatism·Joanna BaldingOliver FitzGerald
May 17, 2008·Journal of Oral Rehabilitation·C Mejersjö, B Wenneberg
May 22, 2009·Cranio : the Journal of Craniomandibular Practice·Jorge A LearretaAndreas C Durst
Dec 5, 2014·Journal of Oral Rehabilitation·C P S HoyuelaJ Natour
Dec 18, 2014·Acta Odontologica Scandinavica·Neveen AhmedPer Alstergren
May 18, 2005·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Atilla ArinciAyşe Karan
May 18, 2001·Oral Diseases·P Alstergren

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
P AlstergrenS Kopp
European Heart Journal Cardiovascular Imaging
Smruti S NalawadiHeart Institute, Cedars-Sinai Medical Center, Los Angeles, California
Kōkūbyō Gakkai zasshi. The Journal of the Stomatological Society, Japan
I SakamotoS Enomoto
© 2022 Meta ULC. All rights reserved