Interleukin-22 in urinary tract disease - new experimental directions

Clinical & Translational Immunology
Molly A Ingersoll, Malcolm R Starkey

Abstract

Interleukin (IL)-22 is expressed by immune cells in the urinary tract and IL-22 receptor is expressed in urothelium and renal tubule cells. IL-22 can be specifically targeted in the urinary tract or conditionally depleted in mice and targeted therapeutically in humans.

References

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Mar 6, 2015·American Journal of Physiology. Renal Physiology·Marc WeidenbuschHans-Joachim Anders
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May 7, 2019·Frontiers in Immunology·Guy J M CameronMalcolm R Starkey

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Citations

Feb 6, 2021·Mucosal Immunology·Bernadette Jones-FreemanMalcolm R Starkey

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