Interleukin-6 polymorphisms modify the risk of periodontitis: a systematic review and meta-analysis.

Journal of Zhejiang University. Science. B
Mei-ying ShaoTao Hu

Abstract

To clarify the association of IL-6 polymorphisms and periodontitis, a meta-analysis of case-control studies and a systemic review were conducted. We performed a literature search using PubMed and Medline database to May 2009, with no restrictions. We also reviewed references from all retrieved articles. Six case-control studies involving 1 093 periodontitis cases and 574 controls were selected for meta-analysis to assess the purported associations between IL-6 polymorphisms and the risk of periodontitis. IL-6 -174 G/C and -572 C/G polymorphisms were included in the present meta-analysis, and the association between IL-6 -6331 T/C polymorphism and the risk of periodontitis was adequately reviewed as well. The present meta-analysis indicates that the IL-6 -174 G allele could not modify the risk of chronic periodontitis, but increased the risk of aggressive periodontitis. And -572 C/G polymorphism is associated with the pathogenesis of periodontitis, including chronic periodontitis or aggressive periodontitis.

References

Dec 1, 1993·Journal of Periodontology·L A CoreyH A Schenkein
Feb 1, 1994·Journal of Periodontology·K TakahashiY Murayama
Feb 12, 1998·Annals of Internal Medicine·J LauC H Schmid
Apr 5, 2000·The Journal of Biological Chemistry·C F TerryF R Green
Apr 18, 2000·Chest·S M Opal, V A DePalo
Apr 21, 2001·European Journal of Human Genetics : EJHG·J AkeyM Xiong
Dec 6, 2001·Nature Reviews. Genetics·G S Cooke, A V Hill
Jul 10, 2002·Periodontology 2000·Jasim M Albandar, Thomas E Rams
Dec 14, 2002·Journal of Periodontology·Laurie K McCauley, Rahime M Nohutcu
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Jun 1, 1955·Annals of Human Genetics·B WOOLF
Mar 18, 2004·Journal of Periodontology·Lydie Izakovicova HollaJiri Vacha
Apr 27, 2004·Periodontology 2000·John J TaylorPeter T Donaldson
Nov 10, 2005·Journal of Periodontology·Bruno G Loos
Nov 24, 2005·Journal of Dental Research·P M BrettM Tonetti
Mar 4, 2006·Journal of Periodontology·Johan C WohlfahrtBryan S Michalowicz
May 12, 2006·Periodontology 2000·Francis J HughesGianluca Martuscelli
Aug 11, 2006·Arthritis Research & Therapy·Tadamitsu Kishimoto
Apr 24, 2007·Journal of Clinical Periodontology·Tellervo TervonenRiitta Karttunen
Feb 14, 2008·Journal of Clinical Periodontology·Luigi NibaliPeter M Brett
Mar 22, 2008·Clinical Chemistry·Andrew J P SmithSteve E Humphries
Apr 3, 2008·Journal of Periodontology·Luigi NibaliFrancesco D'Aiuto
Sep 4, 2008·Journal of Periodontology·Kenneth S Kornman
Aug 5, 2008·Journal of Clinical Periodontology·Georgios K NikolopoulosPantelis G Bagos
Sep 9, 2008·Journal of Clinical Periodontology·Giovanni E SalviNiklaus P Lang
Aug 30, 2008·Journal of Periodontal Research·L NibaliG S Griffiths
Oct 7, 2008·Journal of Periodontology·Lydie Izakovicova HollaJiri Vanek
Oct 11, 2008·Nature Reviews. Cancer·Bostjan SerugaIan F Tannock
Dec 5, 2008·Journal of Periodontology·Dong ShiXiuyun Ren
Jan 1, 2009·International Journal of Oral Science·Stephen R CoatsRichard P Darveau
Jun 1, 2009·International Journal of Oral Science·Xue-Song He, Wen-Yuan Shi
Nov 1, 2005·Journal of Periodontology·Bruno G Loos

❮ Previous
Next ❯

Citations

Jun 13, 2012·Genetic Testing and Molecular Biomarkers·Yi LiuChao You
Aug 8, 2014·Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research·Nitin SharmaMoinak Banerjee
Jun 12, 2013·Journal of Clinical Periodontology·Luigi Nibali
Sep 17, 2013·Journal of Periodontal Research·S C T CorbiR M Scarel-Caminaga
Apr 18, 2014·Periodontology 2000·Alexandre R Vieira, Jasim M Albandar
Jan 22, 2013·Immunobiology·Florença Abdanur StefaniPaula Rocha Moreira
Nov 5, 2016·Archives of Oral Biology·Rafaela ScariotPaula Cristina Trevilatto
Oct 19, 2016·Journal of Clinical Periodontology·Luigi NibaliAlexandre R Vieira
Dec 5, 2012·Brazilian Dental Journal·Ruthinéia Diogénes Alves Uchoa LinsRoseana de Almeida Freitas
Jun 17, 2018·Oral Diseases·Hacer Sahin AydınyurtAbdullah Seckin Ertugrul
Oct 14, 2010·Genetic Testing and Molecular Biomarkers·José Manuel FragosoGilberto Vargas-Alarcón
Jul 1, 2017·Central European Journal of Public Health·Hülya TokerErtan Mahir Korkmaz
Mar 1, 2016·Journal of Alzheimer's Disease : JAD·Sim K SinghraoStJohn Crean
Jul 8, 2020·International Journal of Molecular Sciences·Petra Borilova LinhartovaLydie Izakovicova Holla
Jul 10, 2020·Acta Odontologica Scandinavica·Caio Luiz Bitencourt ReisDaniela Silva Barroso de Oliveira
May 23, 2017·International Journal of Dentistry·Maélson Klever da SilvaDaniel Fernando Pereira Vasconcelos
Jul 6, 2012·Molecular Biology Reports·C M AlbuquerqueE M Bastos
Dec 18, 2020·Journal of Clinical Medicine·Małgorzata KozakAndrzej Pawlik
Sep 1, 2021·Periodontology 2000·Trang NguyenYvonne Kapila

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.