Abstract
From November 1985 to 31 July 1997, 65 pediatric patients underwent heart transplantation at Bambino Gesù Hospital in Rome. Two of them underwent retransplantation, both 6 years after the first transplant. The 67 transplant patients had a mean age of 59 months; 11 were under 1 year of age. Their indications for transplantation were cardiomyopathies (38), lymphocytic myocarditis (8), and congenital heart diseases (19). Two patients of the first group successfully received a combined heart and kidney transplant. The 1-, 5-, and 11-year actuarial survival rates for the 65 patients who underwent heart transplantation were 68%, 62%, and 42%, respectively. In the 1st postoperative year in patients who had had cardiomyopathy, a total of 50 episodes of acute rejection (AR), with one death, occurred (mean 1.7 AR/patient per year +/- 1.5) and, in patients who had had congenital heart diseases, 19 ARs (one death) occurred with a mean of 1.58 AR/patient per year +/- 1.4. The incidence of AR was significantly higher in patients who had had myocarditis with a total of 26 episodes (mean 3.7 AR/patient per year +/- 2) and one death. Rehabilitation of heart transplanted children and infants was complete (NYHA class 1) in 52% of patients of this...Continue Reading
Citations
Sep 1, 2005·Pediatric Cardiology·N R LemanG T Wetzel
Apr 1, 1995·The Annals of Thoracic Surgery·D A FullertonH M Sondheimer
Sep 1, 1995·Journal of the American College of Cardiology·D T HsuL J Addonizio
Sep 4, 1999·The Annals of Thoracic Surgery·K R KanterA M Berg
Jun 1, 1997·The Journal of Pediatrics·G SigfússonS A Webber
Sep 1, 2000·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·D N RosenthalD Bernstein
Jul 9, 2002·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Daniel LeviHillel Laks
Jul 23, 2003·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·William P FiserJonathan J Drummond-Webb
Jun 17, 2000·Progress in Pediatric Cardiology·W R MorrowD C Naftel
Jun 17, 2000·Progress in Pediatric Cardiology·R E ChinnockM Baum
Feb 13, 2001·Archives of Disease in Childhood·H Leonard, R Forsyth
Sep 28, 2010·Heart Failure Clinics·Uwe Kühl, Heinz-Peter Schultheiss
Oct 3, 2001·International Anesthesiology Clinics·K K GalliS C Nicolson
Feb 13, 2003·Pediatric Transplantation·H LeonardJ H Dark