PMID: 7011468Dec 1, 1980Paper

Intermittent pimozide versus fluphenazine decanoate as maintenance therapy in chronic schizophrenia

The British Journal of Psychiatry : the Journal of Mental Science
R G McCreadieJ J Heykants

Abstract

In a double-blind trial, 34 male chronic schizophrenic day-patients or in-patients in a hostel ward continued on fluphenazine decanoate given mostly once fortnightly or were switched to pimozide, given on four days each week. Over nine months relapse rates were similar for both groups, and while fewer patients on pimozide were prescribed antiparkinsonian drugs one quarter developed buccolingual masticatory dyskinesia. Plasma pimozide levels suggested satisfactory drug compliance. Average plasma prolactin levels were within the normal rage for untreated men in one quarter of non-relapsing patients on pimozide and three quarters on fluphenazine.

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Citations

Oct 20, 2001·Science and Engineering Ethics·Adil E ShamooPatricia Langenberg
Feb 19, 1998·Schizophrenia Research·J L Ayuso-Gutiérrez, J M del Río Vega
Jul 25, 2014·Human Psychopharmacology·Takefumi SuzukiMasaru Mimura
Jun 26, 2017·Psychotherapy and Psychosomatics·Guy ChouinardMasaomi Iyo
Jul 2, 2005·Journal of Psychiatric Practice·R A Seckinger, X F Amador
Feb 7, 2018·The Cochrane Database of Systematic Reviews·Hanna BergmanKarla Soares-Weiser
Jan 1, 1990·Acta Psychiatrica Scandinavica. Supplementum·J M Kane
Feb 1, 1995·The British Journal of Psychiatry : the Journal of Mental Science·S Hatcher
Mar 1, 1982·The British Journal of Psychiatry : the Journal of Mental Science·R McCreadieJ Kidd
Jul 25, 2013·The Cochrane Database of Systematic Reviews·Stephanie SampsonClive E Adams
Nov 7, 2013·The Cochrane Database of Systematic Reviews·Meghana Mothi, Stephanie Sampson
Feb 6, 2015·The Cochrane Database of Systematic Reviews·Nicola MaayanClive E Adams

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