Intermittent Pneumatic Compression Enhances Formation of Edema Tissue Fluid Channels in Lymphedema of Lower Limbs

Lymphatic Research and Biology
Marzanna ZaleskaTadeusz Budlewski

Abstract

In lymphedema, tissue fluid steadily accumulates in the subcutaneous space containing loose connective tissue. We documented previously that deformation of the structure of subcutaneous collagen bundles and fat by excess fluid leads to formation of "lakes" and interconnected channels with irregular shape. Since there is no force that could mobilize and propel stagnant fluid to the regions where lymphatics absorb and contract, this task should be taken over by external massage. The most effective in this respect seems to be the sequential intermittent pneumatic compression (IPC). The aim of the study was to observe whether IPC would enhance and accelerate formation of tissue fluid channels. Together with the Biocompression Systems (Moonachie, NJ), we designed a high pressure intermittent compression device and used in it our therapy protocol for patients with obstructive lymphedema of lower limbs. The study was carried out on 18 patients with lymphedema stages II-IV. The IPC was applied daily for 1-2 hours. The follow up time was 24-36 months. Lymphoscintigraphy and immunohistopathology of tissue biopsies were used for evaluation of channel formation process. The forced fluid flow brought about increase of the area of fluid chan...Continue Reading

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Citations

Sep 30, 2017·Lymphatic Research and Biology·Ke LiYi Xin Zhang
Oct 20, 2018·Lymphatic Research and Biology·J Jane Phillips, Susan J Gordon
Jun 13, 2020·Journal of Wound Care·Ambreen ChohanJustine C Whitaker
Jun 29, 2018·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·C Schwahn-SchreiberS Reich-Schupke
Sep 21, 2021·British Journal of Community Nursing·Natalie PhillipsJeanne Everett

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Methods Mentioned

BETA
biopsy

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