Intermittent positive pressure ventilation and high frequency ventilation in dogs with experimental bronchopleural fistulae

Critical Care Medicine
B H HoffW Philips

Abstract

This study evaluated respiratory and cardiovascular responses of canines in whom bilateral bronchopleural fistulae were created surgically, and in whom ventilation was varied between intermittent positive pressure ventilation (IPPV) and high frequency ventilation (HFV). An Emerson prototype ventilator was used for HFV at rates of 300-1400/min at driving pressures of 2.5, 5.0, and 10 psi. Gas exchange was judged by arterial and mixed venous blood gases. Cardiac performance was measured by cardiac index, heart rate, stroke index, stroke work index, systemic and pulmonary vascular pressures and resistances. Ventilation during IPPV with the fistula open resulted in a statistically significant increase in PaCO2 and a decrease in PaO2 when compared to both HFV modes. Variations in cardiac function in these open-chested animals were insignificant for all variables tested except pulmonary artery pressures which rose significantly in the IPPV group.

Citations

Feb 1, 1996·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·J H Devitt, B R Boulanger
Oct 1, 1985·Prostaglandins, Leukotrienes, and Medicine·J ArmengolE G King
Aug 1, 1984·Respiration Physiology·H K Chang, A Harf
Sep 1, 1988·Journal of Medical Engineering & Technology·B Hayes
Sep 1, 1996·Clinics in Chest Medicine·D Ost, T Corbridge
Aug 1, 1986·Anaesthesia and Intensive Care·M R Crawford

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