Internal limiting membrane peeling versus no peeling during primary vitrectomy for rhegmatogenous retinal detachment: A systematic review and meta-analysis

PloS One
Matteo FallicoMichele Reibaldi

Abstract

Internal limiting membrane (ILM) peeling during primary vitrectomy for rhegmatogenous retinal detachment (RRD) prevents the formation of postoperative macular epiretinal membrane (ERM). However, studies that compared vitrectomy with and without ILM peeling for RRD, have reported controversial outcomes. To assess the efficacy of ILM peeling versus non-ILM peeling during vitrectomy for RRD by a systematic review and meta-analysis of published studies. PubMed, Medline, Web of Science, Embase databases, and the Cochrane Library were searched up to April 2018 to identify studies that compared primary vitrectomy with and without ILM peeling for RRD with at least six months follow-up. Primary outcomes were the rate of postoperative ERM formation and mean best corrected visual acuity (BCVA) change after vitrectomy. Rate of recurrence of retinal detachment (RD) was assessed as secondary outcome. Risk ratios (RRs) with 95% confidence intervals (CIs) expressed pooled results for rate of ERM formation and rate of RD recurrence in ILM peeling and non-ILM peeling groups. Pooled results for BCVA change in the two groups were expressed as Weighted Mean Difference (WMD) with 95% CIs. Nine studies, one of which was a randomized controlled trial ...Continue Reading

References

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Oct 20, 2011·BMJ : British Medical Journal·Julian P T HigginsUNKNOWN Cochrane Statistical Methods Group
Jan 5, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Mohamed Gaber Ahmed Mohamed EissaHassan Aly Mortada
Mar 23, 2018·European Journal of Ophthalmology·María José Blanco-TeijeiroAntonio Piñeiro Ces
Apr 6, 2018·American Journal of Ophthalmology·Pauline FoveauJean-Baptiste Conart

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Citations

Aug 5, 2020·Acta Ophthalmologica·Matthew R StarrUNKNOWN Primary Retinal Detachment Outcomes (PRO) Study Group
Aug 25, 2020·Acta Ophthalmologica·Matteo FallicoMichele Reibaldi
Jun 4, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Keissy SousaNuno Lourenço Gomes
May 16, 2020·International Journal of Retina and Vitreous·Mohamed Esmail AbdullahMohamed Farouk Abdelkader
Jan 24, 2020·Retina·Justus G GarwegChristin Gerhardt
Mar 13, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ryo MatobaYuki Morizane
Apr 17, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Justus G Garweg
Aug 6, 2021·PloS One·Shumpei ObataUNKNOWN Japan Retina Vitreous Society Registry Committee
Oct 13, 2020·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Abdussalam M AbdullatifHassan A Mortada

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