Internal models and neural computation in the vestibular system.

Experimental Brain Research
Andrea M Green, Dora E Angelaki

Abstract

The vestibular system is vital for motor control and spatial self-motion perception. Afferents from the otolith organs and the semicircular canals converge with optokinetic, somatosensory and motor-related signals in the vestibular nuclei, which are reciprocally interconnected with the vestibulocerebellar cortex and deep cerebellar nuclei. Here, we review the properties of the many cell types in the vestibular nuclei, as well as some fundamental computations implemented within this brainstem-cerebellar circuitry. These include the sensorimotor transformations for reflex generation, the neural computations for inertial motion estimation, the distinction between active and passive head movements, as well as the integration of vestibular and proprioceptive information for body motion estimation. A common theme in the solution to such computational problems is the concept of internal models and their neural implementation. Recent studies have shed new insights into important organizational principles that closely resemble those proposed for other sensorimotor systems, where their neural basis has often been more difficult to identify. As such, the vestibular system provides an excellent model to explore common neural processing str...Continue Reading

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Citations

Feb 5, 2011·Experimental Brain Research·Jean Laurens, Dora E Angelaki
Jan 27, 2012·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Takeshi SuzukiBill J Yates
Oct 15, 2014·Experimental Brain Research·Sergio Delle MonacheGianfranco Bosco
Sep 21, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Tatyana A YakushevaDora E Angelaki
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Jan 10, 2016·Neuroscience Research·Ryosuke ChibaNobuhiko Haga
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Dec 3, 2020·ELife·Sweta AgrawalJohn C Tuthill

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