Internal urethrotomy in girls and its impact on the urethral intrinsic and extrinsic continence mechanisms

The Journal of Urology
R Kessler, C E Constantinou

Abstract

The cause of incontinence in a group of 11 girls (mean age 18 +/- 3 years) who had undergone internal urethrotomy during childhood was assessed. Urodynamic methods were used to characterize the detrusor, and urethral profiles were performed to identify the impact of the operation on the extrinsic and intrinsic mechanisms of urethral closure. The results show that 4 of 11 patients demonstrated detrusor instability associated with a high voiding flow rate. The average resting urethral closure pressure in all patients showed significant reduction in maximum closure pressure (62 +/- 32 cm. water) when compared to normal age-matched controls. Transmission pressures to coughing demonstrated a high percentage of transmission to the distal and mid urethra (180 +/- 20 per cent). It was concluded that the intrinsic mechanism of urethral continence as measured by the resting urethral pressure profile was compromised by the urethrotomy. However, the extrinsic mechanisms as measured by the transmission values was not affected. On the basis of these findings it is argued that internal urethrotomy compromises the closure mechanisms intrinsic to the urethra. Continence in these patients most likely is maintained by the action of extrinsic fact...Continue Reading

Citations

Jan 1, 1993·Urological Research·W A HübnerE A Tanagho
Feb 15, 2001·The Journal of Urology·T P de JONGM A Vijverberg
Feb 24, 2006·Annals of Biomedical Engineering·Qiyu PengChristos E Constantinou
Mar 31, 2012·Neurourology and Urodynamics·Aart J KlijnTom P V M de Jong

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