Internal validation and comparison of the prognostic performance of models based on six emergency scoring systems to predict in-hospital mortality in the emergency department.

BMC Emergency Medicine
Zahra RahmatinejadHamidreza Reihani

Abstract

Medical scoring systems are potentially useful to make optimal use of available resources. A variety of models have been developed for illness measurement and stratification of patients in Emergency Departments (EDs). This study was aimed to compare the predictive performance of the following six scoring systems: Simple Clinical Score (SCS), Worthing physiological Score (WPS), Rapid Acute Physiology Score (RAPS), Rapid Emergency Medicine Score (REMS), Modified Early Warning Score (MEWS), and Routine Laboratory Data (RLD) to predict in-hospital mortality. A prospective single-center observational study was conducted from March 2016 to March 2017 in Edalatian ED in Emam Reza Hospital, located in the northeast of Iran. All variables needed to calculate the models were recorded at the time of admission and logistic regression was used to develop the models' prediction probabilities. The Area Under the Curve for Receiver Operating Characteristic (AUC-ROC) and Precision-Recall curves (AUC-PR), Brier Score (BS), and calibration plots were used to assess the models' performance. Internal validation was obtained by 1000 bootstrap samples. Pairwise comparison of AUC-ROC was based on the DeLong test. A total of 2205 patients participated ...Continue Reading

References

Apr 1, 1989·Medical Decision Making : an International Journal of the Society for Medical Decision Making·D K McClish, S H Powell
Jul 1, 1987·The American Journal of Emergency Medicine·K J RheeN H Willitis
Nov 1, 1984·Critical Care Medicine·J R Le GallD Villers
Oct 6, 2001·QJM : Monthly Journal of the Association of Physicians·C P SubbeL Gemmel
Mar 16, 2011·Critical Care : the Official Journal of the Critical Care Forum·Nesrin O Ghanem-ZoubiHaim Bitterman
Jun 17, 2011·The New England Journal of Medicine·Arthur L Kellermann, Ricardo Martinez
Sep 15, 2018·The American Journal of Emergency Medicine·Zahra RahmatinejadSaeid Eslami

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