Internally driven control of reaching movements: a study on a proprioceptively deafferented subject

Brain Research Bulletin
Fabrice R SarlegnaJ Blouin

Abstract

We investigated the possibility of controlling reaching movements on the sole basis of central mechanisms, i.e., without peripheral feedback on hand and target positions. A deafferented subject (GL) and control subjects reached with the unseen hand for a straight-ahead target that could be displaced laterally at movement onset. The shifted target was continuously or briefly lit, or not visible. In this latter condition, a beep from either side of subjects' head single-handedly signaled the change in the movement goal, so that movements could only be controlled through an internal representation of the memorised target position. Compared to controls, GL showed quantitatively similar corrections (77% of the target displacement, on an average) and similar reaction times to the target shift (mean = 516 ms), regardless of target visual information. These results highlight a remarkable capacity for controlling reaching movements on the sole basis of internally driven processes. On the other hand, trajectories in double-step trials differed drastically between GL and controls. Controls' trajectories were composed of two segments, the second of which brought the hand directly toward the displaced target. The patient produced three-segm...Continue Reading

References

Jun 1, 1991·Electroencephalography and Clinical Neurophysiology·M FalkensteinL Blanke
Jan 1, 1991·Vision Research·B Bridgeman, L Stark
Mar 1, 1988·Canadian Journal of Psychology·D Elliott
Sep 1, 1982·Brain : a Journal of Neurology·J C RothwellC D Marsden
Sep 29, 1995·Science·D M WolpertM I Jordan
Feb 1, 1995·Canadian Journal of Physiology and Pharmacology·C Ghez, R Sainburg
Dec 1, 1993·Canadian Journal of Experimental Psychology = Revue Canadienne De Psychologie Expérimentale·J BlouinM Fleury
May 14, 1999·Experimental Brain Research·C BardO Martin
Feb 15, 2000·Experimental Brain Research·B L Day, I N Lyon
Jan 5, 2002·Canadian Journal of Experimental Psychology = Revue Canadienne De Psychologie Expérimentale·D A WestwoodE A Roy
May 22, 2002·Experimental Brain Research·Jean BlouinGabriel M Gauthier
Oct 2, 2002·Experimental Brain Research·Helen JohnsonPatrick Haggard
Jun 28, 2003·Experimental Brain Research·Fabrice SarlegnaGabriel M Gauthier
Nov 15, 2003·Journal of Neurophysiology·Liana E BrownRobert L Sainburg
Dec 1, 1950·Journal of Comparative and Physiological Psychology·R W SPERRY
Mar 10, 2004·Experimental Brain Research·Fabrice SarlegnaGabriel M Gauthier
May 6, 2004·Experimental Brain Research·Michael A KhanEric Buckolz
Jun 24, 2004·Journal of Neurophysiology·J D CrawfordJ J Marotta
Aug 6, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·S AllainF Vidal
Jan 22, 2005·Journal of Neurophysiology·Robert A ScheidtFerdinando A Mussa-Ivaldi
Mar 29, 2005·Nature Neuroscience·Samuel J Sober, Philip N Sabes
Nov 25, 2005·Experimental Brain Research·Leia B BagesteiroRobert L Sainburg

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Citations

Apr 11, 2009·Cerebral Cortex·Philippe S ArchambaultAlexandra Battaglia-Mayer
Aug 25, 2012·Cerebral Cortex·Alexandra Battaglia-MayerRoberto Caminiti
May 17, 2013·The European Physical Journal. E, Soft Matter·Pierre LegreneurMichel Laurin
Jan 31, 2016·Neuroscience Letters·Hannah Z LefumatFabrice R Sarlegna
Aug 14, 2009·The Journal of Physiology·Alexandra ReichenbachJean-Pierre Bresciani
Sep 15, 2009·Trends in Cognitive Sciences·Michel Desmurget, Angela Sirigu
May 26, 2009·Brain Research Bulletin·Marie-Claude Hepp-ReymondRumyana Kristeva
Jul 28, 2010·Brain Research·Jared MedinaH Branch Coslett
Feb 5, 2011·Acta Psychologica·Michel GuerrazJean Blouin
Jul 6, 2014·Vision Research·Brendan D Cameron, Joan López-Moliner
Jul 20, 2014·Vision Research·Fabrice R Sarlegna, Pratik K Mutha
Aug 22, 2009·Neuropsychologia·Fabrice R SarlegnaJean-Louis Vercher
Jan 22, 2009·Neuropsychologia·Stefano FerrainaRoberto Caminiti
Mar 13, 2012·Neuropsychologia·Stephanie A H JonesDenise Y P Henriques
Jul 6, 2016·Frontiers in Human Neuroscience·Lucilla CardinaliAlessandro Farnè
Mar 18, 2016·PLoS Computational Biology·Cevat Üstün
Aug 26, 2006·Neuroreport·Pierre-Michel BernierIan M Franks
May 7, 2019·Journal of Vision·Dimitris VoudourisKatja Fiehler
Sep 17, 2010·Journal of Neurophysiology·V Gritsenko, J F Kalaska
Feb 3, 2012·Journal of Neurophysiology·L BringouxL Mouchnino
Apr 18, 2019·Journal of Neurophysiology·Nicoletta RisiRobert A Scheidt
Nov 8, 2014·Journal of Neurophysiology·Carlijn Andrea VernooijRaymond Francis Reynolds
May 4, 2017·Journal of Neuroengineering and Rehabilitation·Alexis R KruegerRobert A Scheidt
Mar 20, 2018·Computational Intelligence and Neuroscience·Roberto ColomboFabrizio Pisano
Apr 5, 2018·PloS One·Hanna GertzDimitris Voudouris
Jun 25, 2020·Journal of Neurophysiology·S A L JayasingheR L Sainburg
Jan 1, 2018·Multisensory Research·Rachel GoodmanLuc Tremblay
Jul 28, 2020·Frontiers in Neuroscience·Cécile R ScottoLucette Toussaint
Jun 16, 2017·Journal of Neurophysiology·Mohsen OmraniPaul D Cheney

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