PMID: 5909788Mar 18, 1966

Internally perfused axons: effects of two different anions on ionic conductance

W J AdelmanJ P Senft


Voltage-clamizped giant axons of squid, internally perfused with potassiumt chloride solutions, showed reduced initial transient memnbrane conductance to voltage and increased overall (leakage) conductance. Unclamtped axons showed reduced action and resting potentials. Ionic conductances and memtbrane potentials were maintained or restored by perfusion with potassiuwn fluoride solutions. As much as 90 percent of internal fluoride could be replaced with chloride without alterationt of normal properties of membrane.


May 3, 1975·The Journal of Membrane Biology·L BinstockH Lecar
May 4, 2004·Molecular and Cellular Neurosciences·Bertrand CostePatrick Delmas
Nov 1, 1967·The Journal of General Physiology·F J Brinley, L J Mullins
Aug 1, 1968·The Journal of General Physiology·E Rojas, M Canessa-Fischer
Jun 1, 1974·The Journal of General Physiology·T Begenisich, C Lynch
May 1, 1978·The Journal of General Physiology·K S LeeA M Brown
Jun 1, 1980·The Journal of General Physiology·D C Eaton, M S Brodwick
Aug 1, 1969·Journal of Cellular Physiology·P G ShragerA Strickholm

Related Concepts

Chloride Ion Level
Electrophysiology (Science)
Nerve Conduction Function
Science of Neurochemistry

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