PMID: 7519315Aug 1, 1994Paper
International Commission for Protection Against Environmental Mutagens and Carcinogens. Deoxyribonucleoside triphosphate levels: a critical factor in the maintenance of genetic stability
Mutation Research
B A KunzJ A Reidy
Abstract
DNA precursor pool imbalances can elicit a variety of genetic effects and modulate the genotoxicity of certain DNA-damaging agents. These and other observations indicate that the control of DNA precursor concentrations is essential for the maintenance of genetic stability, and suggest that factors which offset this control may contribute to environmental mutagenesis and carcinogenesis. In this article, we review the biochemical and genetic mechanisms responsible for regulating the production and relative amounts of intracellular DNA precursors, describe the many outcomes of perturbations in DNA precursor levels, and discuss implications of such imbalances for sensitivity to DNA-damaging agents, population monitoring, and human diseases.
References
Nov 1, 1976·Journal of Bacteriology·J L Bousque, N Sicard
Jan 1, 1979·Molecular & General Genetics : MGG·L PrakashS Prakash
May 3, 1975·Lancet·E R GiblettL K Diamond
Nov 1, 1976·Mutation Research·P Maier, W Schmid
Jul 1, 1978·Cell·L J GudasD W Martin
Nov 21, 1978·Biochimica Et Biophysica Acta·J E HeinzeE Freese
Apr 1, 1978·Journal of Bacteriology·S J Hochhauser, B Weiss
Jun 1, 1978·Canadian Journal of Genetics and Cytology. Journal Canadien De Génétique Et De Cytologie·H Traut
Mar 5, 1979·Molecular & General Genetics : MGG·E A WurtzJ E Boynton
Dec 1, 1977·Cell·D Perlman, J A Huberman
Jun 1, 1978·Cell·B UllmanD W Martin
Jul 1, 1977·Antimicrobial Agents and Chemotherapy·C S GentherC C Smith
Aug 1, 1977·Genetical Research·R J PinneyJ T Smith
Mar 20, 1978·Molecular & General Genetics : MGG·B J Barclay, J G Little
Aug 24, 1978·Nature·J H MillerP J Farabaugh
Sep 1, 1978·Mutation Research·P J DaviesJ M Parry
Jan 1, 1979·Mutation Research·A J Norin, E P Goldschmidt
Mar 28, 1979·Biochimica Et Biophysica Acta·P J Abbott, R Saffhill
Jan 31, 1979·Molecular & General Genetics : MGG·C S NewlonS K Walter
Jan 1, 1979·Cold Spring Harbor Symposia on Quantitative Biology·E M Witkin, I E Wermundsen
Jan 1, 1978·Drug and Chemical Toxicology·D MathesonR Carrano
Aug 1, 1979·Environmental Health Perspectives·A J Griffiths
Sep 1, 1979·Canadian Journal of Genetics and Cytology. Journal Canadien De Génétique Et De Cytologie·W R Bruce, J A Heddle
Genetic studies of the lac repressor. IV. Mutagenic specificity in the lacI gene of Escherichia coli
Dec 15, 1977·Journal of Molecular Biology·C Coulondre, J H Miller
Apr 1, 1978·Journal of Bacteriology·F Makino, N Munakata
Jul 26, 1979·Biochimica Et Biophysica Acta·A A FrancisJ D Regan
Jul 1, 1979·Mutation Research·A R Peterson, H Peterson
Sep 1, 1979·Human Genetics·M Keck, I Emerit
Aug 10, 1978·Nature·M O Bradley, N A Sharkey
Dec 1, 1977·Mutation Research·S M Galloway
Nov 30, 1978·Nature·A R PetersonC Heidelberger
Jan 1, 1978·Hereditas·S KnuutilaA De La Chapelle
Jan 1, 1975·Advances in Cancer Research·S M Sieber, R H Adamson
Apr 1, 1976·Mutation Research·B Herbold, W Buselmaier
Jul 15, 1976·Virology·J W Little
Jul 5, 1976·Molecular & General Genetics : MGG·J M ParryW E Evans
May 1, 1975·Journal of General Microbiology·R W Buick, W J Harris
Jul 1, 1977·Genetics·W E Williams, J W Drake
Apr 16, 1975·Biochimica Et Biophysica Acta·P BalgavýR Turek
Mar 1, 1976·Mutation Research·N V LuchnikV G Ovchinnikova
Jan 16, 1992·Nature·H Maki, M Sekiguchi
Mar 1, 1992·Journal of Virology·J H ElderT R Phillips
Mar 11, 1992·American Journal of Obstetrics and Gynecology·C E ButterworthV Baker
May 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·S ChellappanJ R Nevins
Jul 16, 1992·Nature·S J WeintraubD C Dean
Mar 1, 1992·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·M SikorskaP R Walker
Sep 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·E M McIntoshR H Haynes
Sep 29, 1992·Biochemistry·B T Eger, S J Benkovic
Oct 1, 1992·Journal of Bacteriology·M L Michaels, J H Miller
Nov 1, 1992·Journal of Virology·R B PylesR L Thompson
❮ Previous
Next ❯
Citations
Jun 9, 1999·International Journal of Cancer. Journal International Du Cancer·H MiyachiY Ando
Feb 14, 2002·Archives of Biochemistry and Biophysics·Peter Reichard
Feb 8, 2006·Cancer Chemotherapy and Pharmacology·Lars Petter JordheimCharles Dumontet
Sep 1, 1995·Mutation Research·L R Ferguson, W A Denny
Feb 19, 1996·Mutation Research·P MuskP G Parsons
Aug 17, 1996·Mutation Research·B A Kunz
Jan 1, 1996·Journal of Photochemistry and Photobiology. B, Biology·E K HenriksenG Brunborg
Jun 21, 2005·Pharmacology & Therapeutics·Sally Anne HunsuckerJozef Spychala
Dec 7, 2000·Mutation Research·M J ArmstrongS M Galloway
Feb 6, 2002·Mutation Research·Stella A Martomo, Christopher K Mathews
Nov 11, 1996·Mutation Research·R Fahrig
Jun 26, 1998·Mutation Research·S K GreenwoodS M Galloway
Jul 7, 1999·Mutation Research·R F BrandaJ A Nicklas
Feb 2, 2000·Leukemia Research·N Gattermann
Aug 29, 2003·Molecular Immunology·Marilyn DiazChristopher K Mathews
Mar 15, 2001·Antiviral Research·P Wutzler, R Thust
Oct 16, 2001·Journal of Pharmaceutical and Biomedical Analysis·J ChiF T Aweeka
Mar 4, 2000·Free Radical Biology & Medicine·K Bialkowski, K S Kasprzak
Jan 14, 2000·Mutation Research·L HendersonM Aardema
Mar 22, 2002·Mutation Research·P H M Lohman
Jun 30, 2011·Nature Communications·Pauline ChabosseauMounira Amor-Guéret
Oct 12, 2004·Nature Structural & Molecular Biology·Karl-Magnus LarssonPär Nordlund
Feb 13, 1999·Molecular Microbiology·M Z Humayun
Jul 19, 2000·Proceedings of the National Academy of Sciences of the United States of America·C RampazzoV Bianchi
Feb 7, 2012·Nucleosides, Nucleotides & Nucleic Acids·Vishal V Gandhi, David C Samuels
Jun 15, 2006·Antioxidants & Redox Signaling·Stéphanie Gon, Jon Beckwith
Feb 3, 2005·DNA and Cell Biology·Ann Saada
May 23, 2003·Cold Spring Harbor Symposia on Quantitative Biology·B GeorgievaR Rothstein
May 22, 2004·European Journal of Biochemistry·Hanne FrederiksenBirgitte Munch-Petersen
Oct 6, 1998·Annual Review of Biochemistry·A Jordan, P Reichard
Jul 9, 2004·Genome Biology·John L Hartman, Nicholas P Tippery
Feb 8, 2014·Cell Death & Disease·L D WeeksS L Gerson
Jan 25, 2006·Proceedings of the National Academy of Sciences of the United States of America·Zhen ZhangMingxia Huang
Feb 6, 2007·Proceedings of the National Academy of Sciences of the United States of America·Zhen ZhangMingxia Huang
Oct 1, 2013·Mutagenesis·Siv Osterman GolkarSiamak Haghdoost
Mar 24, 2005·Proceedings of the National Academy of Sciences of the United States of America·Shiwei SongChristopher K Mathews
Nov 26, 2008·Human Molecular Genetics·Luis C LópezMichio Hirano
Mar 18, 2000·Antimicrobial Agents and Chemotherapy·L JiangP K Rathod
Aug 3, 2001·Journal of Virology·M JaniniF E McCutchan
Jan 13, 2006·Nucleic Acids Research·Lauren SeipleJames T Stivers
Feb 1, 2007·Nucleic Acids Research·Shinya TakahashiToshiaki Katada
Sep 18, 2007·Eukaryotic Cell·Javier BotetMaría A Santos
Sep 9, 2008·Journal of Bacteriology·Damian GawelRoel M Schaaper
Mar 14, 2009·Nucleic Acids Research·Scott D McCullochThomas A Kunkel
Dec 17, 2009·Nucleic Acids Research·Paola FerraroVera Bianchi
Mar 11, 2010·Nucleic Acids Research·Dinesh KumarAndrei Chabes
Oct 22, 2010·Nucleic Acids Research·Dinesh KumarAndrei Chabes
Oct 22, 2010·The Journal of Biological Chemistry·Christelle DupouyPierre Alexandre Kaminski
May 13, 2011·Journal of Virology·Héctor MorenoVerónica Martín
May 18, 2011·Nucleic Acids Research·Peter M WilsonRobert D Ladner
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