International consensus statement for the use of botulinum toxin treatment in adults and children with neurological impairments--introduction

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
A EsquenaziAnthony B Ward

Abstract

Botulinum neurotoxin (BoNT) is most commonly used to reduce focal over-activity in skeletal muscle, although newer indications such as management of drooling, pain and tremor are emerging. Treatment of spasticity incorporating BoNT is usually part of an integrated multidisciplinary rehabilitation programme. Prior to initiating this therapy, specific functional limitations, goals and expected outcomes of treatment should be discussed with the patient/carers. Muscle selection and the order/priority of treatment should be agreed. Treatment goals may involve increasing active or passive function or the avoidance of secondary complications or impairment progression. This paper describes the basic science mechanisms of the action of BoNT and subsequent nerve recovery and introduces a supplement comprising the best available evidence and expert opinion from international panels on questions of assessment, indications, BoNT regimen, adjunctive therapy, expected outcomes and recommended monitoring. Speciality areas reviewed include Paediatric Lower Limb Hypertonicity, Paediatric Upper Limb Hypertonicity, Adult Lower Limb Hypertonicity, Adult Upper Limb Hypertonicity, Cervical Dystonia, Drooling and Pain and Niche Indications. There is g...Continue Reading

References

Apr 1, 1992·Developmental Medicine and Child Neurology·P A Blasco
Apr 1, 1992·Australian Dental Journal·B K YoungT C Crewe
Mar 1, 1985·Journal of the American Academy of Child Psychiatry·J Spurlock
May 23, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·M K HouserA J Lees
Mar 17, 1999·Proceedings of the National Academy of Sciences of the United States of America·A de PaivaJ O Dolly
Sep 9, 2000·Archives of Internal Medicine· Habib-ur-Rehman
Nov 5, 2002·Current Pain and Headache Reports·Geoffrey Sheean
Jan 2, 2003·Pediatrics·Terence D SangerUNKNOWN Task Force on Childhood Motor Disorders
Jan 1, 1959·Journal of Neurosurgery·E L FOLTZA A WARD
Sep 27, 2003·Journal of Substance Abuse Treatment·Amelia M Arria, UNKNOWN TOPPS-II Interstate Cooperative Study Group
Mar 18, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Markus Naumann, Wolfgang Jost
Jul 22, 2004·Current Medical Research and Opinion·Markus Naumann, Joseph Jankovic
Feb 17, 2005·Muscle & Nerve·Jean-Michel Gracies
Feb 17, 2005·Muscle & Nerve·Jean-Michel Gracies
Apr 1, 2005·Disability and Rehabilitation·A D PandyanG R Johnson
Apr 6, 2006·Physiotherapy Research International : the Journal for Researchers and Clinicians in Physical Therapy·Stephen Ashford, Lynne Turner-Stokes
May 30, 2006·Archives of Physical Medicine and Rehabilitation·Catherine C TurkelMitchell F Brin
Nov 23, 2006·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·J O Dolly, K R Aoki
Nov 23, 2007·Disability and Rehabilitation·Dirk Dressler, Reiner Benecke
Nov 23, 2007·Disability and Rehabilitation·Lynne Turner-Stokes, Stephen Ashford
May 7, 2008·Neurology·D M SimpsonUNKNOWN Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
May 28, 2008·Pain Practice : the Official Journal of World Institute of Pain·Louise C Jeynes, Charles A Gauci
Jan 23, 2009·Current Opinion in Pharmacology·Silvia BenemeiPierangelo Geppetti
Feb 7, 2009·Journal of Rehabilitation Medicine·Jörg WisselNiko Tieranta
Feb 19, 2009·Movement Disorders : Official Journal of the Movement Disorder Society·Antonio Emanuele EliaAlberto Albanese
Apr 7, 2009·Toxicon : Official Journal of the International Society on Toxinology·Rami BursteinStephen Silberstein
May 28, 2009·Toxicon : Official Journal of the International Society on Toxinology·Alberto EsquenaziAlberto Albanese
Aug 14, 2009·Journal of Advanced Nursing·Heather WilliamsLynne Turner-Stokes

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Citations

Jul 17, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·J OlverUNKNOWN Cerebral Palsy Institute
Apr 1, 2014·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Joseph J FantuzzoJeffrey M Karp
Apr 12, 2013·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Roberta RavenniAlberto Mazza
Apr 24, 2012·Journal of the American Medical Directors Association·Kuen LamChristine Leung
Oct 26, 2011·Parkinsonism & Related Disorders·Raymond L RosalesHubert H Fernandez
Feb 5, 2013·Toxicon : Official Journal of the International Society on Toxinology·Steven B Abrams, Mark Hallett
Jun 7, 2011·Topics in Stroke Rehabilitation·Christina Marciniak
Jun 28, 2016·PM & R : the Journal of Injury, Function, and Rehabilitation·David M SimpsonIb Odderson
Oct 25, 2013·Singapore Medical Journal·Yee Sien NgKeng He Kong
Jan 19, 2017·American Journal of Physical Medicine & Rehabilitation·Maria D Gonzalez-LSantiago Suso-Vergara
Jun 26, 2014·Arquivos de neuro-psiquiatria·Elizabeth M A Barasnevicius Quagliato
Jun 7, 2013·The Cochrane Database of Systematic Reviews·Marina DemetriosShane McSweeney
Sep 18, 2012·Stroke; a Journal of Cerebral Circulation·Gerard E Francisco, John R McGuire
Oct 23, 2016·PM & R : the Journal of Injury, Function, and Rehabilitation·John McGuireMichael W O'Dell
Nov 10, 2013·Australian Health Review : a Publication of the Australian Hospital Association·Kathy KuipersKathy Grudzinskas
Sep 4, 2019·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Anna CastagnaMarina Ramella
Mar 12, 2017·Neurology·Jörg WisselUNKNOWN TOWER study investigators
Mar 7, 2020·Current Medical Research and Opinion·Hitoshi KagayaRyuji Kaji
Apr 11, 2012·Current Opinion in Otolaryngology & Head and Neck Surgery·Nina SquiresJohn Rowson
Jun 25, 2020·PM & R : the Journal of Injury, Function, and Rehabilitation·Alvin H IpPatricia B Mills
Mar 7, 2020·Health and Quality of Life Outcomes·Klemens FheodoroffDavid M Simpson
Nov 6, 2020·PM & R : the Journal of Injury, Function, and Rehabilitation·Alberto EsquenaziGerard E Francisco
Apr 16, 2020·Annals of Physical and Rehabilitation Medicine·Djamel BensmailDavid M Simpson
Feb 9, 2021·Frontiers in Neurology·Petr KaňovskýChristina Marciniak
Nov 23, 2016·Journal of the Neurological Sciences·Raymond L RosalesArlene R Ng

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