International human xenotransplantation inventory

Transplantation
Antonino SgroiLuc Noel

Abstract

Xenotransplantation carries inherent risks of infectious disease transmission to the recipient and even to society at large, and it should only be carried out with strict regulation and oversight. In collaboration with the International Xenotransplantation Association, the University Hospital Geneva, and the World Health Organization, an international inventory has been established (www.humanxenotransplant.org) aiming to collect basic data on all types of currently ongoing or recently performed xenotransplantation procedures in humans. We collected information from publications in scientific journals, presentations at international congresses, the internet, and declarations of International Xenotransplantation Association members on xenotransplantation procedures in humans performed during the past 15 years. We identified a total of 29 human applications of xenotransplantation, including 7 that were currently ongoing. Procedures involved transplantation of xenogeneic cells, i.e., islets of Langerhans, kidney cells, chromaffin cells, embryonic stem cells, fetal and adult cells from various organs or extracorporeal perfusion using hepatocytes, liver, spleen, or kidney. The treatments were performed in 12 different countries, 9 of...Continue Reading

References

Mar 1, 1997·Nature Medicine·C PatienceR A Weiss
Sep 29, 2001·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·G V MazariegosJ F Patzer
May 10, 2002·The International Journal of Artificial Organs·E MorsianiA D Pinna
Nov 29, 2002·The International Journal of Artificial Organs·M P van de KerkhoveR A F M Chamuleau
Apr 22, 2004·Xenotransplantation·Megan SykesMichael A Rees
Sep 1, 2005·European Journal of Endocrinology·Rafael A Valdés-GonzálezDavid J G White
Dec 6, 2005·Cerebrovascular Diseases·J van Gijn, A Algra
Oct 25, 2006·Xenotransplantation·Leo BuhlerLuc Noel
Mar 29, 2007·PLoS Medicine·Muhammad M Mohiuddin

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Citations

Sep 27, 2015·International Journal of Surgery·Henk-Jan Schuurman
Jan 17, 2013·Xenotransplantation·David K C CooperMassimo Trucco
Dec 17, 2010·Xenotransplantation·Mårten K J Schneider, Jörg D Seebach
Apr 14, 2012·Xenotransplantation·Mårten K J Schneider, Jörg D Seebach
Jul 22, 2014·Xenotransplantation·Donald G HarrisRichard N Pierson
Oct 1, 2015·MMWR. Morbidity and Mortality Weekly Report·Misha P RobynDebra Blog
Oct 25, 2011·Lancet·Burcin EkserDavid K C Cooper
Dec 17, 2014·International Journal of Surgery·Sebastian G MichelKumaran Shanmugarajah
Nov 23, 2012·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·M GolrizA Mehrabi
Jul 8, 2011·Transfusion Medicine·C E Butler, E L Dickens
May 7, 2020·Xenotransplantation·David K C Cooper
Jun 17, 2020·Xenotransplantation·Linda Scobie, Henk-Jan Schuurman
Jan 26, 2012·Proceedings·David K C Cooper
Aug 16, 2013·The Journal of Immunology : Official Journal of the American Association of Immunologists·Linda ScobieJean-Paul Soulillou
Dec 2, 2017·Journal of Human Genetics·Nozomu Takata, Mototsugu Eiraku
Aug 7, 2020·Progress in Retinal and Eye Research·Chang Ho YoonMee Kum Kim

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