International Initiative for Outcomes (INFO) for vitiligo: workshops with patients with vitiligo on repigmentation

The British Journal of Dermatology
V EleftheriadouK Ezzedine

Abstract

There is no cure or firm clinical recommendations for the treatment of vitiligo. One of the main issues is the heterogeneity of outcome measures used in randomized controlled trials for vitiligo. To define successful repigmentation from the patients' point of view and to propose how and when repigmentation should be evaluated in clinical trials in vitiligo. We conducted three workshops with patients with vitiligo and their parents or caregivers. Workshop 1 was held at World Vitiligo Day (Detroit, MI), workshop 2 at the University of Texas Southwestern Medical Center and workshop 3 at the Vitiligo and Pigmentation Institute of Southern California, University of California. Seventy-three participants were recruited. Consensus on the following questions was achieved unanimously: (i) the definition of 'successful repigmentation' was 80-100% of repigmentation of a target lesion and (ii) both an objective and a subjective scale to measure repigmentation should be used. This was the largest patients' outcomes workshop. We followed the guidance from the CSG-COUSIN and the Vitiligo Global Issues Consensus Group. Our recommendations to use percentage of repigmentation quartiles (0-25%, 26-50%, 51-79%, 80-100%) and the Vitiligo Noticeabil...Continue Reading

References

Oct 15, 2010·The Journal of Investigative Dermatology·Jochen SchmittUNKNOWN Harmonizing Outcome Measurements in Eczema (HOME) Delphi panel
Sep 19, 2012·Archives of Dermatology·Charlotte VrijmanPhyllis I Spuls
Feb 4, 2015·Pigment Cell & Melanoma Research·Viktoria EleftheriadouUNKNOWN Vitiligo Global Issues Consensus Group
Feb 2, 2016·The Journal of Investigative Dermatology·Nanja van GeelReinhart Speeckaert
Sep 18, 2016·Clinics in Dermatology·Viktoria Eleftheriadou, Khaled Ezzedine
Nov 20, 2016·Pigment Cell & Melanoma Research·Emily Y GanUNKNOWN VGICC
Feb 15, 2018·The British Journal of Dermatology·J KottnerUNKNOWN International Cochrane Skin Group Core Outcome Set Initiative (CSG-COUSIN) group

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Citations

Mar 2, 2019·The British Journal of Dermatology·A Wolkerstorfer
Apr 5, 2019·Pigment Cell & Melanoma Research·Nanja van GeelUNKNOWN participants of the Rome International VGICC /VIS Workshop
Jul 30, 2020·The British Journal of Dermatology·V S NarayanA Wolkerstorfer
Feb 18, 2020·The British Journal of Dermatology·N van GeelK Ezzedine
Oct 3, 2020·The British Journal of Dermatology·K S ThomasUNKNOWN UK Dermatology Clinical Trials Network’s HI-Light Vitiligo Trial Team
Jan 7, 2021·The Journal of Dermatology·Christina Bergqvist, Khaled Ezzedine
Mar 18, 2021·International Journal of Dermatology·Sonia Chavez-AlvarezAlejandra Villarreal-Martinez
Jul 21, 2021·Clinical Reviews in Allergy & Immunology·Yinghan WangChunying Li
Mar 11, 2020·Dermatology : International Journal for Clinical and Investigative Dermatology·Christina Bergqvist, Khaled Ezzedine
Jul 12, 2021·Journal of the American Academy of Dermatology·Jung Min BaeIltefat H Hamzavi

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