International Partnership for Therapeutic Drug Development of NTDs by DNDi

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
Haruki YamadaChris Brünger

Abstract

The Drugs for Neglected Diseases initiative (DNDi), with headquarters in Geneva, is a non-profit drug research and development (R&D) organization and Product Development Partnership (PDP) which was established in 2003 by 7 founding organizations such as Médecins Sans Frontières (MSF), the Pasteur Institute, The Specific Programme for Research and Training in Tropical Diseases (WHO-TDR), etc. DNDi has worked mainly on the development of new treatments for neglected tropical diseases (NTDs), which is difficult to achieve under market economy conditions. DNDi has promoted overall drug discovery research including the screening of drug candidates, hit to lead, lead optimization, pre-clinical and clinical studies in the area of infectious diseases with a focus on malaria, sleeping sickness (human African trypanosomiasis; HAT), Chagas disease, leishmaniasis, filarial diseases and pediatric formulations for HIV treatment. DNDi's achievements include the development of novel therapies based on patient needs through innovative partnerships with over 130 organizations in industry, government, academia, and public institutions around the world. To date, DNDi has registered 6 novel treatments adapted to the needs of patients in poor countr...Continue Reading

References

May 16, 2006·Lancet·Pierre Chirac, Els Torreele

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Citations

Jul 9, 2020·Expert Opinion on Investigational Drugs·Nieves Martínez-PeinadoJulio Alonso-Padilla

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