Interobserver agreement in diagnosing liver involvement in hereditary hemorrhagic telangiectasia by Doppler ultrasound

Ultrasound in Medicine & Biology
E BuscariniA Zambelli

Abstract

The purpose was to evaluate interobserver agreement on Doppler ultrasonographic (US) diagnosis of liver vascular malformations (VMs) in hereditary hemorrhagic teleangiectasia (HHT) and on their severity grading. During the interobserver agreement study, three observers with at least seven years of specific experience using Doppler US for the diagnosis of liver VMs, judged about the presence/absence of liver VMs and their severity on a set of images and videoclips. Interobserver agreement was estimated with kappa statistics. One-hundred ten cases were reviewed during interobserver study (80 cases with liver VMs, 30 without). Very good kappa values of the interobserver agreement were found for all pairs concerning the distinction between presence and absence of hepatic VMs. All observers demonstrated excellent sensitivity and specificity in identifying hepatic VMs, with their respective areas under the curve ranging from 0.97 to 0.99. Interobserver agreement among the three investigators in staging the hepatic VMs in HHT patients was moderate (Kendall's coefficient of concordance = 0.26). Study results indicate that Doppler US diagnosis of liver VMs in HHT has a high degree of agreement among ultrasonographers; a moderate agreeme...Continue Reading

References

Dec 1, 1991·Statistics in Medicine·D G Altman
Jul 1, 1986·Journal of Clinical Ultrasound : JCU·M ZoliE Pisi
Dec 1, 1995·AJR. American Journal of Roentgenology·H NaganumaO Masamune
Nov 1, 1994·AJR. American Journal of Roentgenology·E BuscariniM Piantanida
Sep 28, 2000·The New England Journal of Medicine·G Garcia-TsaoR I White
Apr 30, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Martin CaselitzMichael Gebel
Dec 3, 2003·Radiology·Amato Antonio Stabile IanoraGiuseppe Angelelli
May 18, 2004·Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie·K OcranW Wermke
Sep 16, 2004·Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie·E BuscariniA Zambelli
Dec 23, 2004·The Korean Journal of Hepatology·Joon Koo Han, Se Hyung Kim
Jun 1, 2005·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·E BuscariniA Zambelli
Oct 13, 2006·Liver International : Official Journal of the International Association for the Study of the Liver·Elisabetta BuscariniMarie E Faughnan

❮ Previous
Next ❯

Citations

Oct 31, 2015·Journal of Hepatology·UNKNOWN European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu
Oct 31, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Guadalupe Garcia-Tsao, Karen L Swanson
Jul 11, 2018·Abdominal Radiology·Elisabetta BuscariniGuido Manfredi
Sep 8, 2020·Annals of Internal Medicine·Marie E FaughnanRoberto Zarrabeitia
May 12, 2020·Journal of Medical Ultrasonics·Hiroko NaganumaMasahiro Ogawa

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie
E BuscariniA Zambelli
Liver International : Official Journal of the International Association for the Study of the Liver
E BuscariniM E Faughnan
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Rodica GinculJean-Christophe Saurin
© 2021 Meta ULC. All rights reserved