PMID: 8946294Dec 1, 1996Paper

Interobserver and intraobserver variability in the detection of glaucomatous progression of the optic disc

Journal of Glaucoma
A L ColemanD S Minckler

Abstract

To evaluate the potential value of obtaining follow-up stereoscopic photographs on glaucoma suspects in identifying progressive optic nerve damage. Nineteen sets of stereoscopic optic disc photographs, reflecting one eye from each of 19 patients at two time points, were selected from the records of subjects enrolled in the Glaucoma Screening Study. By consensus, three experts judged 13 of these eyes to have progressive glaucomatous optic nerve damage. Four other ophthalmologists who were masked to the expert panel evaluation then assessed glaucomatous progression in the same eyes. They were asked to evaluate glaucomatous progression in three ways: first, by drawing the optic nerve head appearance from initial stereoscopic photographs and later comparing their own drawings to follow-up stereoscopic photographs; second, by comparing serial stereoscopic photographs directly; and third, by comparing drawings of the optic nerve head made by another examiner to the follow-up photographs. Neither sensitivity nor specificity was consistently better for serial stereoscopic photographs than for drawings. Individual ophthalmologist agreement rates with the expert panel's determinations of progression were 23-62% when examiners compared th...Continue Reading

Citations

Aug 8, 2009·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·E M Hoffmann
Oct 6, 2000·American Journal of Ophthalmology·C BowdL M Zangwill
Dec 4, 2001·American Journal of Ophthalmology·M T NicolelaR P LeBlanc
Mar 8, 2000·American Journal of Ophthalmology·S C PatelA L Robin
Aug 6, 2002·Survey of Ophthalmology·Curtis E MargoZuber D Mulla
Jun 12, 1999·The British Journal of Ophthalmology·A Azuara-BlancoJ J Augsburger
Mar 24, 2000·The British Journal of Ophthalmology·G N ShuttleworthJ P Diamond
Oct 22, 2008·Investigative Ophthalmology & Visual Science·Shaban DemirelChris A Johnson
Apr 6, 2013·Investigative Ophthalmology & Visual Science·Andrew J TathamFelipe A Medeiros
Jul 29, 2009·Optometry : Journal of the American Optometric Association·Michael CymborMatthew Mastrine
Aug 2, 2011·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Jean-Claude MwanzaDonald L Budenz
Sep 16, 2010·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Nathan M RadcliffeRobert Ritch
Dec 26, 2006·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Vasudha ErraguntlaAlex V Levin
Mar 5, 2005·Ophthalmology·Anne L ColemanSusannah Rowe
Oct 18, 2005·American Journal of Ophthalmology·Richard K ParrishUNKNOWN Ocular Hypertension Treatment Study Group
Jun 30, 2015·Computer Methods and Programs in Biomedicine·V Bolón-CanedoM F Chiang
Feb 6, 2015·International Journal of Clinical Practice·J ScheetzM E Morris
Oct 6, 2010·Ophthalmology·Jean-Claude MwanzaUNKNOWN Cirrus Optical Coherence Tomography Normative Database Study Group

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.