Interobserver reliability and diagnostic performance of Chiari II malformation measures in MR imaging--part 2.

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
Niels GeerdinkReinier A Mullaart

Abstract

Brain MR imaging is essential in the assessment of Chiari II malformation in clinical and research settings concerning spina bifida. However, the interpretation of MR images of the malformation is not always straightforward. Morphometric analyses of the extent of Chiari II malformation may improve the assessment. In an attempt to select appropriate morphometric measures for this purpose, we investigated the interobserver reliability and diagnostic performance of several morphometric measures of Chiari II malformation on MR images. Brain MR images of 79 children [26 with open spinal dysraphism, 17 with closed spinal dysraphism, and 36 without spinal dysraphism; mean age 10.6 (SD 3.2; range, 6-16) years] were evaluated. All children had been assessed for Chiari II malformation (defined as cerebellar herniation in combination with open spinal dysraphism; n = 23). Three observers blindly and independently reviewed the MR images for 21 measures of the cerebellum, brainstem, and posterior fossa in three planes. The interobserver reliability was assessed by an agreement index (AI = 1 - RRE) and the diagnostic performance by receiver operating characteristic analyses. Reliability was good for most measures, except for the degree of her...Continue Reading

References

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Citations

Mar 11, 2017·AJNR. American Journal of Neuroradiology·U D NagarajB M Kline-Fath
Aug 5, 2017·Neurologia Medico-chirurgica·Nobuhito Morota
Apr 6, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Leopoldo Mandic Ferreira FurtadoTúlio Ramos Cavalcanti

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