Interplay between DNA supercoiling and transcription elongation

Transcription
Jie Ma, Michelle D Wang

Abstract

Transcription-coupled DNA supercoiling has been shown to be an important regulator of transcription that is broadly present in the cell. Here we review experimental work which shows that RNA polymerase is a powerful torsional motor that can alter DNA topology and structure, and DNA supercoiling in turn directly affects transcription elongation.

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Citations

May 22, 2016·Biochemical and Biophysical Research Communications·Soumitra GhoshValakunja Nagaraja
Oct 21, 2016·Nature Reviews. Molecular Cell Biology·Yves PommierJohn L Nitiss
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Dec 13, 2016·Biophysics Reviews·Yeonee Seol, Keir C Neuman
Jul 24, 2021·Physical Review Letters·Xiang GaoMichelle D Wang
Sep 22, 2021·Immunological Reviews·Caroline KaiserAndrew S Koh

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