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Interplay of TGFb superfamily members governs optic fissure closure

bioRxiv

Oct 24, 2014

Stephan HeermannJoachim Wittbrodt

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Abstract

The optic fissure is a gap in the developing vertebrate eye and must be closed as development proceeds. A persisting optic fissure is referred to as coloboma, a major cause for blindness in children. Multiple factors have been linked to coloboma formation, however, the actual process of...read more

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  • Interplay of TGFb superfamily members governs optic fissure closure

    bioRxiv

    Oct 24, 2014

    Stephan HeermannJoachim Wittbrodt

    PMID: 990010652

    DOI: 10.1101/010652

    Abstract

    The optic fissure is a gap in the developing vertebrate eye and must be closed as development proceeds. A persisting optic fissure is referred to as coloboma, a major cause for blindness in children. Multiple factors have been linked to coloboma formation, however, the actual process of...read more

    3

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