PMID: 644544Feb 1, 1978

Interpretation of lung function tests in the sickle-cell haemoglobinopathies

Thorax
G J MillerR J Gilson

Abstract

Prediction equations have been evolved for the assessment of vital capacity, total lung capacity, and the single breath carbon monoxide transfer factor in haemoglobin SS and haemoglobin SC disease. These relationships take account of the growth disorder and anaemia in the sickle-cell states. The results suggest that, in the clinically stable state, any effects of alveolar capillary sickling and haemoconcentration and any altered reactivity of haemoglobins S and C with the test gas are of no significance for clinical respiratory physiology. Sex differences in lung function appear independent of haemoglobin type.

References

Jul 1, 1974·The British Journal of Ophthalmology·P I CondonG R Serjeant
Nov 1, 1972·American Journal of Ophthalmology·P I Condon, G R Serjeant
Apr 24, 1965·British Medical Journal·N L JONES, J F GOODWIN

Citations

Apr 28, 2005·International Journal of Clinical Practice·Z HijaziH Al-Habashi
Mar 1, 1991·Archives of Disease in Childhood·E F BowenG R Serjeant
Nov 26, 2013·Paediatric Respiratory Reviews·Anastassios C Koumbourlis
Mar 1, 1993·The Journal of Pediatrics·P PianosiA L Coates
May 7, 2014·American Journal of Hematology·Eduard J van BeersPaul Bresser
Jan 1, 1989·International Journal of Health Services : Planning, Administration, Evaluation·A Torres, M R Reich
Sep 6, 2002·Oncogene·Edward H Hinchcliffe, Greenfield Sluder
Jan 1, 1983·Journal of Mathematical Biology·D A Lauffenburger, C R Kennedy
Mar 1, 1995·Postgraduate Medical Journal·E D LehmannD N Croft
Mar 1, 1995·Postgraduate Medical Journal·O M Jolobe

Related Concepts

Anemia, Sickle Cell
Carbon Monoxide
Hemoglobin C
Hemoglobin C Disease
Hemoglobin SS
Lung
Lung Volume Measurements
African Continental Ancestry Group

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