PMID: 9434917Jan 22, 1998Paper

Interpretation of the pulmonary artery occlusion pressure in mechanically ventilated patients with large respiratory excursions in intrathoracic pressure

Intensive Care Medicine
J D Hoyt, James W Leatherman

Abstract

To assess the reliability of the pulmonary artery occlusion pressure (Ppao) when respiratory excursions in intrathoracic pressure are prominent. We studied 24 critically ill patients who had 15 mm Hg or more of respiratory excursion in their Ppao tracing. Large respiratory excursions resulted from respiratory muscle activity that persisted despite sedation and mechanical ventilation in the assist-control mode. From the Ppao tracing, the end-expiratory and mid-point values were recorded; the latter was measured halfway between end-expiration and the nadir due to inspiratory triggering. The Ppao was then re-measured after administration of a non-depolarizing muscle relaxant. Medical intensive care unit of a university-affiliated teaching hospital. The difference between the pre-relaxation end-expiratory Ppao and the relaxed Ppao was larger than the difference between the pre-relaxation mid-point Ppao and the relaxed Ppao (11 +/- 5 vs 3 +/- 3 mm Hg, p < 0.01). In 21 of 24 (88%) cases, the relaxed Ppao was more closely approximated by the mid-point Ppao than by the end-expiratory Ppao. The difference between the end-expiratory Ppao and the relaxed Ppao increased as the amount of respiratory excursion increased (r = 0.51; p < 0.01)....Continue Reading

References

Nov 1, 1978·Anesthesiology·R E BerryhillL A Rauscher
Feb 1, 1992·Journal of Applied Physiology·M Takata, J L Robotham
Dec 1, 1990·Journal of Applied Physiology·M TakataJ L Robotham
Nov 1, 1986·The American Review of Respiratory Disease·J J MariniV Lamb
Aug 1, 1986·Journal of Applied Physiology·E Bar-YishayJ R Rodarte
Aug 1, 1982·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·J J MariniJ Butler
Jan 1, 1995·American Journal of Respiratory and Critical Care Medicine·R GiulianiV M Ranieri
Oct 1, 1994·American Journal of Respiratory and Critical Care Medicine·A ChandraJ J Marini
Jan 1, 1993·The American Review of Respiratory Disease·J Hansen-FlaschenE C Raps
Jan 1, 1959·Journal of Applied Physiology·J MEAD, E A GAENSLER
Mar 1, 1964·Journal of Applied Physiology·J MILIC-EMILIJ M TURNER

❮ Previous
Next ❯

Citations

Sep 13, 2007·Intensive Care Medicine·Ahmad S QureshiJames W Leatherman
Mar 31, 2010·Intensive Care Medicine·Belén CabelloJordi Mancebo
Jun 19, 2013·General Thoracic and Cardiovascular Surgery·Takuro KometaniIchiro Yoshino
Jun 27, 2003·Journal of Cardiothoracic and Vascular Anesthesia·Katherine P Grichnik, Steven E Hill
Jan 5, 2001·The Journal of Cardiovascular Nursing·E K Daily
Apr 3, 2008·The Journal of Cardiovascular Nursing·Susan K Frazier, Glenda J Skinner
Apr 18, 2009·Critical Care Medicine·Henry E Fessler
Aug 3, 1999·American Journal of Respiratory and Critical Care Medicine·T Al-KharratC A Manthous
Jul 19, 2006·Critical Care : the Official Journal of the Critical Care Forum·Sarah HeenenJean-Louis Vincent
Nov 23, 2006·The Surgical Clinics of North America·Patricio M Polanco, Michael R Pinsky
Jan 9, 2004·Clinics in Chest Medicine·Michael R Pinsky
Sep 27, 2007·Journal of Intensive Care Medicine·Elizabeth L DaughertyBarry D Fuchs
Dec 8, 2004·Seminars in Cardiothoracic and Vascular Anesthesia·Katherine P Grichnik, Thomas A D'Amico
Jan 13, 2010·International Anesthesiology Clinics·Michael J Andritsos, Kyung W Park

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.