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Interrogating Amyloid Aggregates using Fluorescent Probes

Chemical Reviews

Nov 2, 2019

Amir AliyanAngel A Martí

Abstract

Amyloids are a broad class of proteins and peptides that can misfold and assemble into long unbranched fibrils with a cross-β conformation. These misfolding and aggregation events are associated with the onset of a variety of human diseases, among them, Alzheimer's disease, Parkinson's ...read more

Mentioned in this Paper

Fluorescent Dyes
Study
In Vivo
Alzheimer's Disease
Thioflavin T
Protein Aggregation, Pathological
Protein Conformation
Amyloid
Structure
Parkinson Disease
6
1
34
Paper Details
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Interrogating Amyloid Aggregates using Fluorescent Probes

Chemical Reviews

Nov 2, 2019

Amir AliyanAngel A Martí

PMID: 31675223

DOI: 10.1021/acs.chemrev.9b00404

Abstract

Amyloids are a broad class of proteins and peptides that can misfold and assemble into long unbranched fibrils with a cross-β conformation. These misfolding and aggregation events are associated with the onset of a variety of human diseases, among them, Alzheimer's disease, Parkinson's ...read more

Mentioned in this Paper

Fluorescent Dyes
Study
In Vivo
Alzheimer's Disease
Thioflavin T
Protein Aggregation, Pathological
Protein Conformation
Amyloid
Structure
Parkinson Disease
6
1
34

Similar Papers Found In These Feeds

Proteostasis

Proteostasis enables the maintenance of protein homeostasis via modulation of protein translation, enhancement of chaperone capacity and the prompt clearance of misfolded proteins. It is affected in several neurodegenerative diseases. Here is the latest research.

Misfolding & Aggregation Diseases

Misfolding and aggregation of proteins can lead to several diseases. For instance, misfolding of prion or tau proteins are associated with several neurodegenerative diseases. Here is the latest research on diseases caused by protein misfolding and aggregation.

Related Papers

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry

Vibrational Approach to the Dynamics and Structure of Protein Amyloids

Molecules : a Journal of Synthetic Chemistry and Natural Product ChemistryJanuary 10, 2019
Haoqian LiDeguo Du
Protein Science : a Publication of the Protein Society

A brief overview of amyloids and Alzheimer's disease

Protein Science : a Publication of the Protein SocietyJuly 22, 2014
Sian-Yang Ow, Dave E Dunstan
Paper Details
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