Interrogating target-specificity by parallel screening of a DNA-encoded chemical library against closely related proteins

Chemical Communications : Chem Comm
Raphael M FranziniDario Neri

Abstract

Parallel affinity screening of a DNA-encoded chemical library against rat, bovine and human serum albumin allowed the identification of small-molecule ligands with distinctive binding specificities to the individual proteins.

References

Apr 21, 2004·Nature Biotechnology·Samu MelkkoDario Neri
Jul 5, 2005·Bioorganic & Medicinal Chemistry Letters·K Ingrid SprinzAndrew D Hamilton
Sep 30, 2006·Chembiochem : a European Journal of Chemical Biology·Hugo D UrbinaNicolas Winssinger
Oct 9, 2007·Journal of the American Chemical Society·S Jarrett WrennPehr B Harbury
Nov 13, 2008·Proceedings of the National Academy of Sciences of the United States of America·Luca MannocciDario Neri
Jan 7, 2009·Journal of the American Chemical Society·Margit Haahr HansenNils Jakob Vest Hansen
Aug 4, 2009·Nature Chemical Biology·Matthew A ClarkBarry A Morgan
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Jun 22, 2011·Angewandte Chemie·Nina SvensenMark Bradley
May 17, 2012·Chemistry : a European Journal·Markus LeimbacherDario Neri
Apr 11, 2013·Journal of Medicinal Chemistry·Jeremy S DischRobert B Perni
Nov 16, 2013·Journal of the American Chemical Society·Yizhou LiXiaoyu Li
Mar 29, 2014·Accounts of Chemical Research·Raphael M FranziniJörg Scheuermann
Aug 7, 2014·Chemical Communications : Chem Comm·Cheng CaoXiaoyu Li

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Citations

Jan 29, 2016·ACS Chemical Biology·Hazem SalamonAndreas Brunschweiger
Dec 23, 2015·Bioorganic & Medicinal Chemistry Letters·Sofia BarluengaNicolas Winssinger
Mar 18, 2016·Nature Protocols·Willy DecurtinsJörg Scheuermann
Jun 18, 2015·ACS Combinatorial Science·Raphael M FranziniDario Neri
Jun 11, 2015·Journal of Medicinal Chemistry·Florent SamainRaphael M Franzini
Feb 26, 2016·Journal of Medicinal Chemistry·Raphael M Franzini, Cassie Randolph
Dec 10, 2016·Nature Reviews. Drug Discovery·Robert A GoodnowAnthony D Keefe
Dec 30, 2016·Chembiochem : a European Journal of Chemical Biology·Lik Hang Yuen, Raphael M Franzini
Jul 18, 2017·Nature Communications·Carl A MachuttaGhotas Evindar
Oct 22, 2019·Chemical Communications : Chem Comm·Thomas KodadekPaige Dickson
Feb 27, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Justin M RectenwaldKenneth H Pearce
May 22, 2019·Expert Opinion on Drug Discovery·Guixian ZhaoXiaoyu Li
Apr 24, 2021·Chembiochem : a European Journal of Chemical Biology·Yiran Huang, Xiaoyu Li
Mar 12, 2019·Journal of the American Chemical Society·Lik Hang YuenRaphael M Franzini

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