Interspecific variation in UV defense mechanisms among temperate freshwater fishes

Photochemistry and Photobiology
Mark H Olson, David L Mitchell

Abstract

An important step in predicting the effects of future increases in UV radiation (UVR) is to evaluate the mechanisms that organisms use to prevent and repair DNA damage and determine how those mechanisms influence UVR sensitivity. Damage is prevented to varying degrees through photoprotection and repaired via two main pathways: nucleotide excision repair and photoenzymatic repair. At present, little is known about the generality or similarity of these defenses among temperate freshwater fishes. We used laboratory experiments to compare UVR defense mechanisms among five freshwater fish species representing four families and three orders. Purified DNA, freeze-killed larvae and live larvae were exposed to UVB radiation for 12 h in the presence or absence of photorepair radiation. After exposure, we quantified frequencies of cyclobutane pyrimidine dimers in each exposure treatment. All five species used photoprotection and proportional decreases in dimer frequency were similar for all species. Evidence of excision repair was also found for all species but proportional decreases in photoproduct frequencies varied among species. Finally, evidence of photoenzymatic repair was found for only two of the five species.

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Citations

Apr 11, 2013·Aquatic Toxicology·Aude KienzlerAlain Devaux
Aug 15, 2008·Photochemistry and Photobiology·Sandra J ConnellyDavid L Mitchell
Jan 24, 2009·Photochemistry and Photobiology·Eveliina MarkkulaIlmari E Jokinen
Dec 17, 2009·Photochemistry and Photobiology·David Mitchell, Becky Brooks
Dec 8, 2011·Photochemistry and Photobiology·Eeva-Riikka VehniäinenAimo Oikari
May 13, 2008·International Journal of Radiation Biology·Andrew J Rainbow, Natalie J Zacal
Oct 11, 2008·Journal of Photochemistry and Photobiology. B, Biology·Qiaoxiang DongKurt R Svoboda
May 11, 2016·Journal of Photochemistry and Photobiology. B, Biology·C BraunU E Siebeck
Dec 15, 2017·Biology Letters·Simon VittIngolf P Rick
Feb 28, 2009·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·David L MitchellMark H Olson
Feb 27, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Isabel A S F CostaA K Gamperl
Jan 22, 2011·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·D-P HäderR C Worrest

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Methods Mentioned

BETA
scintillation spectrometry

Software Mentioned

PER

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