Interstitial brachytherapy of peri-orificial skin carcinomas on the face

Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
E RioB Dreno

Abstract

Purpose. - To analyse outcomes after interstitial brachytherapy of facial periorificial skin carcinomas. Patients and methods. - We performed a retrospective analysis of 97 skin carcinomas (88 basal cell carcinomas (BCCs), 9 squamous cell carcinomas (SCCs)) of the nose, periorbital areas and ears from 40 previously untreated patients (group 1) and 57 patients who had undergone surgery (group 2). The average dose was 55 Gy [50-65] in group 1 and 52 Gy [50-60] in group 2 (mean implantation times: 79 and 74 hours respectively). We calculated survival rates and assessed functional and cosmetic results de visu. Results. - Median age was 71 years [17-97]. There were 29 T1, 8 T2, 1 T3 and 2 Tx tumors in group 1. Tumors were<2 cm in group 2. Local control was 92.5% in group 1 and 88% in group 2 (median follow-up: 55 months [6-132]). Five-year disease-free survival was better in group 1 (91% [75-97]) than in group 2 (80% [62-90]), P=0.23. Of the 34 patients whose results were re-assessed, eight presented pruritus or epiphora. One group 2 patient had an impaired eyelid aperture. Cosmetic results were better in group 1 than in group 2, with respectively 72% (8/11) vs 52% (12/23) of good results and 28 (3/11) vs. 43% (10/23) of fair result...Continue Reading

References

Mar 1, 1991·International Journal of Radiation Oncology, Biology, Physics·F F LiuP Fitzpatrick
Apr 1, 1991·International Journal of Radiation Oncology, Biology, Physics·C A Perez
Dec 1, 1990·Journal of the American Academy of Dermatology·M SextonM E Maloney
Jan 1, 1990·International Journal of Radiation Oncology, Biology, Physics·J M CrookB Pierquin
Nov 1, 1988·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J J MazeronS Danczak
Oct 1, 1986·International Journal of Radiation Oncology, Biology, Physics·J J MazeronB Pierquin
Jan 1, 1987·British Journal of Plastic Surgery·J D Richmond, R M Davie
Aug 1, 1985·Plastic and Reconstructive Surgery·G C Burget, F J Menick
Oct 1, 1968·American Journal of Surgery·S C BinderD Catlin
Oct 1, 1983·American Journal of Surgery·R ByersB Schwarz
Apr 1, 1984·International Journal of Radiation Oncology, Biology, Physics·N J DalyP F Combes
Jan 1, 1983·The Journal of Dermatologic Surgery and Oncology·H Goldschmidt, W K Sherwin
May 1, 1983·Archives of Dermatology·N Dubin, A W Kopf
Mar 1, 1994·The British Journal of Dermatology·C B KoC Nicholson
Oct 1, 1993·British Journal of Plastic Surgery·C M Lawrence
Jun 1, 1997·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·S SabanathanA J Mearns
Nov 8, 2001·International Journal of Radiation Oncology, Biology, Physics·J LockeC A Perez
Jan 5, 2002·International Journal of Radiation Oncology, Biology, Physics·Akmal SafwatJolyon H Hendry
Jul 9, 2002·The British Journal of Dermatology·Y ScrivenerB Cribier
Jul 6, 2004·Annales de dermatologie et de vénéréologie·F Stéphan, J Revuz
Jul 28, 2004·International Journal of Radiation Oncology, Biology, Physics·Carlos ConillAntonio Vilalta

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