Interstitial fluid flow in tendons or ligaments: a porous medium finite element simulation

Medical & Biological Engineering & Computing
S L ButlerR Vanderby

Abstract

The purpose of this study is to describe interstitial fluid flow in axisymmetric soft connective tissue (ligaments or tendons) when they are loaded in tension. Soft hydrated tissue was modelled as a porous medium (using Darcy's Law), and the finite element method was used to solve the resulting equations governing fluid flow. A commercially available computer program (FiDAP) was used to create an axisymmetric model of a biomechanically tested rat ligament. The unknown variables at element nodes were pressure and velocity of the interstitial fluid (Newtonian and incompressible). The effect of variations in fluid viscosity and permeability of the solid matrix was parametrically explored. A transient loading state mimicking a rat ligament mechanical experiment was used in all simulations. The magnitude and distribution of pressure, stream lines, shear (stress) rate, vorticity and velocity showed regular patterns consistent with extension flow. Parametric changes of permeability and viscosity strongly affected fluid flow behaviour. When the radial permeability was 1000 times less than the axial permeability, shear rate and vorticity increased (approximately 5-fold). These effects (especially shear stress and pressure) suggested a s...Continue Reading

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Citations

Sep 29, 2007·Biomechanics and Modeling in Mechanobiology·Michael LavagninoRoger C Haut
Mar 25, 2009·Biomechanics and Modeling in Mechanobiology·Scott R LucasRobert S Salzar
Feb 3, 2011·Annals of Biomedical Engineering·Gabriel ParentEve Langelier
Dec 21, 2004·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Carlos Bonifasi-ListaJeffrey A Weiss
Apr 1, 2010·Journal of Biomechanical Engineering·Peter Galie, Robert L Spilker
Nov 16, 2013·Journal of Biomechanical Engineering·Shawn P Reese, Jeffrey A Weiss
Dec 17, 2008·Journal of Applied Physiology·Trevor J LujanJeffrey A Weiss
Jun 6, 2014·Journal of the Royal Society, Interface·R P TuckerM S Thompson
Dec 3, 2005·Journal of Biomechanics·Jeffrey A Weiss, Benjamin J Maakestad
Aug 20, 2014·Journal of Biomechanics·Aaron M SwedbergJeffrey A Weiss
Aug 9, 2005·Medical Engineering & Physics·Jeffrey A WeissNikhil S Phatak
Jun 8, 2004·Journal of Biomechanical Engineering·Ergin Tönük, M Barbara Silver-Thorn
Dec 15, 2017·Journal of Biomechanical Engineering·Brianne K Connizzo, Alan J Grodzinsky
May 5, 2005·Journal of Biomechanical Engineering·Paul S RobinsonLouis J Soslowsky
Oct 12, 2005·Plastic and Reconstructive Surgery·Kenton D FongJames Chang
May 17, 2019·Fluids and Barriers of the CNS·Esmée VendelElizabeth C M de Lange
Apr 27, 2018·Journal of the Royal Society, Interface·Mathew BaldwinAndrew Carr
Mar 22, 2019·Proceedings of the National Academy of Sciences of the United States of America·Ehsan BanVivek B Shenoy
Aug 18, 2017·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Michelle WallAlbert J Banes
Feb 25, 2017·Journal of Biomechanics·Brianne K Connizzo, Alan J Grodzinsky

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