PMID: 8941530Nov 1, 1996Paper

Interstitial fluid, plasma protein, colloid, and leukocyte uptake into initial lymphatics

Journal of Applied Physiology
Fumitaka IkomiG W Schmid-Schonbein

Abstract

Lymphatics serve to remove from the interstitium a range of materials, including plasma proteins, colloid materials, and cells. Lymph flow rates can be enhanced by periodic tissue compression or venous pressure elevation, but little is known to what degree enhancement of lymph flow affects material transport. The objective was to examine the uptake of plasma proteins, a colloidal perflubron emulsion (LA-11063, mean particle diameter = 0.34 micron), and leukocytes into lymphatics. Prenodal collecting lymphatics in the lower hindlimb of rabbits were cannulated with and without foot massage and after elevation of venous pressure (40 mmHg). The average lymph flow rates were elevated approximately 22-fold by the skin massage but only about threefold by venous pressure elevation. Lymph-to-plasma protein concentration ratio remained unchanged by the massage but decreased significantly after venous pressure elevation. Lymph colloid concentration and leukocyte counts were elevated on average 47 and 8.5 times, respectively, by foot massage, but both decreased after venous pressure elevation. These results suggest that skin movement by massage and elevation of the venous pressure lead to opposite lymph transport kinetics of protein, collo...Continue Reading

References

May 1, 1975·The American Journal of Physiology·B W Zweifach, J W Prather
Jan 1, 1992·Biomaterials, Artificial Cells, and Immobilization Biotechnology : Official Journal of the International Society for Artificial Cells and Immobilization Biotechnology·J G RiessE G Schutt
Feb 1, 1991·International Journal of Radiation Biology·C ThomasM Guichard
Oct 1, 1990·Physiological Reviews·G W Schmid-Schönbein
Jan 1, 1971·Microvascular Research·M Intaglietta, B W Zweifach
Jan 1, 1971·Microvascular Research·B W Zewifach, M Intaglietta
Oct 1, 1970·British Journal of Plastic Surgery·J S CalnanL M Taylor
Dec 1, 1970·The American Journal of Physiology·D G Garlick, E M Renkin
Sep 1, 1995·Clinics in Dermatology·F Ikomi, G W Schmid-Schönbein
Aug 31, 1938·The Journal of Experimental Medicine·P D McMaster, R J Parsons

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Jan 9, 2014·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Elaheh RahbarDavid C Zawieja
Apr 9, 2015·American Journal of Physiology. Endocrinology and Metabolism·Cathryn M KolkaRichard N Bergman
Oct 1, 2014·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Gunnar SchützHubertus Pietsch
Apr 26, 2015·Bulletin of Mathematical Biology·Charles HeppellGiles Richardson
Feb 15, 2019·Journal of Veterinary Internal Medicine·Melanie D Craven, Robert J Washabau
Sep 1, 2004·Springer Seminars in Immunopathology·Gwendalyn J RandolphVeronique Angeli
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Mar 8, 2008·The Journal of Physiological Sciences : JPS·Takashi NagaiToshio Ohhashi
Dec 31, 2004·Lymphatic Research and Biology·Geert W Schmid-Schönbein
Sep 11, 2010·The American Journal of Surgical Pathology·Melissa P PulitzerKlaus Busam
Oct 29, 2003·Cancer Control : Journal of the Moffitt Cancer Center·James W JakubDouglas S Reintgen
Aug 2, 2005·Nature Reviews. Immunology·Gwendalyn J RandolphMelody A Swartz
Sep 26, 2009·Lymphatic Research and Biology·Zoë L S BrookesNicola J Brown
Sep 30, 2017·Lymphatic Research and Biology·Ke LiYi Xin Zhang
May 2, 2018·Annual Review of Fluid Mechanics·James E Moore, Christopher D Bertram
Jan 14, 2020·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Fumitaka Ikomi, Sumiyo Hiruma
Nov 20, 2012·Bulletin of Mathematical Biology·Charles HeppellTiina Roose
Sep 8, 2017·Journal of Biomedical Materials Research. Part a·Rebecca L ThompsonJoe Tien
Feb 11, 2020·Frontiers in Physiology·Yen-Chun Ho, R Sathish Srinivasan
Jun 11, 2004·Seminars in Oncology·J W JakubD S Reintgen
Aug 15, 2021·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Cornelia Sigrid Lissi MüllerClaudia Pföhler

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