Interstitial irradiation for unresectable carcinoma of the lung.

The Annals of Thoracic Surgery
B S HilarisE J Beattie

Abstract

From 1963 to 1971, 105 patients with histologically proved cancer of the lung were explored at Memorial Hospital and underwent interstitial implantation using encapsulated sources of radon 222 (53 patients) or iodine 125 (52 patients). These lung cancers were considered unresectable because of extension of the disease into the mediastinum with fixation or invasion of the major vessels, trachea, and esophagus or chest wall involvement. No apical lesions, which have a better prognosis, are included in this review. Sixty-nine patients had epidermoid cancer, 24 had adenocarcinoma, and the remaining 12 had various other histological types. All patients were staged according to the criteria proposed by the American Joint Committee using the TNM definitions (standing for tumor, nodes, and metastasis). Local control was obtained in 8 of 10 patients (80% with clinical Stage I and II unresectable cancers of the lung and in 44 of the 95 (46%) with clinical Stage III lung cancer. The two-year survival was 50% for Stages I and II and 7% for Stage III. Five patients have survived for five years or more. The complications, disease-free interval, local recurrences, distant metastases, and survival are presented and indications for this type of...Continue Reading

References

Jan 1, 1958·Cancer·E E CLIFFTONH H SELBY

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Citations

Sep 1, 1987·The Japanese Journal of Surgery·E J Beattie, N M Raskin
Aug 1, 1996·The Annals of Thoracic Surgery·B MeunierB Launois
Apr 13, 2010·International Journal of Radiation Oncology, Biology, Physics·Athanasios ColoniasDavid S Parda
May 1, 1990·The Annals of Thoracic Surgery·J W LewisD J Magilligan
Dec 1, 1994·The Annals of Thoracic Surgery·B O Anderson, M E Burt
Jan 1, 1981·The Annals of Thoracic Surgery·P McCormackN Martini
Jan 11, 1992·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·T C LoM H Leibenhaut
Jan 1, 1992·Acta neurochirurgica·C B Ostertag, F W Kreth
Jan 1, 1980·Acta Radiologica. Oncology·I I RosenC A Kelsey
Jan 1, 1990·The Annals of Thoracic Surgery·D B Skinner

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