Interstitial Keratitis with Corneal Perforation as the Presenting Sign of Systemic Tuberculosis

Ocular Immunology and Inflammation
Sonam YangzesJagat Ram

Abstract

Background: Ocular surface and corneal involvement in tuberculosis is seldom seen. We report a patient of pulmonary and presumed ocular tuberculosis with immune keratitis along with corneal perforation as the presenting signs.Methods: A middle-aged male presented with stromal keratitis, deep corneal vascularization, and two corneal perforations. Necrotic Mantoux test and cavitary lesion on computerized tomography of the chest clinched the diagnosis of tuberculosis-related interstitial keratitis.Results: Tubercular interstitial keratitis was successfully managed with antitubercular therapy, oral and topical steroids while cyanoacrylate glue was used to seal the corneal perforations.Conclusions: Although corneal involvement is uncommon in ocular tuberculosis, in patients with interstitial keratitis who respond poorly to conventional therapy, a possibility of systemic tuberculosis should be considered in endemic countries.

References

May 29, 1998·Cornea·G S SchwartzE J Holland
Mar 19, 1999·International Ophthalmology Clinics·C M Knox, D S Holsclaw
May 29, 2010·The British Journal of Ophthalmology·Ritu AroraJawaharlal Goyal
Mar 30, 2013·Eye & Contact Lens·Saurabh KamalRuchi Goel
Jan 24, 2015·Ocular Immunology and Inflammation·Vishali GuptaKhalid F Tabbara

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Citations

Jan 25, 2021·Experimental Eye Research·Ruchi ShahAlexander V Ljubimov

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