Interstitial lung disease in coppersmiths in high serum copper levels

Biological Trace Element Research
Canan Eren DagliFatma Inanc Tolun

Abstract

Coppersmith is a worker who uses copper most commonly for the production of kitchen appliances in Turkey. This is an ancient occupation practiced for centuries in Turkey. Our objective was to investigate the prevalence of parenchymal lung diseases among coppersmiths in Kahramanmaras city in Turkey. Thirty coppersmiths were included to the study, and they all signed an informed consent. Demographics, spirometric test results and high-resolution computed tomography (HRCT) scans, and blood samples were obtained. Laboratory analysis of the serum samples showed that serum copper levels of the subjects were 0.93 +/- 0.14 mg/L. Serum copper level in control group was found as 0.70 +/- 0.14 mg/L, and it was significantly different between the two groups (p < 0.05). Of 30 coppersmiths, 17 HRCT findings are abnormal and seen with diffuse parenchymal interstitial lung disease pattern-ten (58.8%) respiratory bronchiolitis interstitial lung disease, five (29.4%) nonspecific interstitial pneumonia, and two (11.8%) usual interstitial pneumonia. The most prevalent HRCT pattern was micronodular pattern in workers. This is the first field study reporting the radiologic findings of coppersmiths and effect of the occupation on lung diseases.

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Citations

Jan 12, 2012·The Annals of Occupational Hygiene·Tim ThompsonM Leigh Ackland
Nov 17, 2010·Biological Trace Element Research·Abdullah Cetin TanrikuluYilmaz Palanci
Sep 2, 2011·Biological Trace Element Research·Abdurrahman AbakayMustafa Ayhan
Oct 6, 2021·International Archives of Occupational and Environmental Health·Marwa Mohammed Fouad, Mona Abdallah Ramadan

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